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Chemical Structure| 50996-12-8 Chemical Structure| 50996-12-8

Structure of 50996-12-8

Chemical Structure| 50996-12-8

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Product Details of [ 50996-12-8 ]

CAS No. :50996-12-8
Formula : C5H6N4O4
M.W : 186.13
SMILES Code : CN1C(N)=C([N+]([O-])=O)C(NC1=O)=O

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Application In Synthesis of [ 50996-12-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 50996-12-8 ]

[ 50996-12-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 50996-12-8 ]
  • [ 6972-82-3 ]
YieldReaction ConditionsOperation in experiment
With ammonium hydroxide; sodium dithionite; In methanol; at 60℃; for 3h; General procedure: Sodium nitrite (1.3g, 19.3mmol) was added in small portions to a stirred solution of the 5,6-diamino-1-methylpyrimidine-2,4(1H,3H)-dione derivatives (12.9mmol) in glacial acetic acid (30mL), the color changed from light red to blue, orange or crimson. The reaction mixture was stirred for about 5h at ambient temperature. The colorized sediment was collected by filtration, washed with water, and dried in vacuo to afford 73.5percent of nitrosated product. To a stirred mixture nitroso compound (2.7g, 9.5mmol) in 25mL methanol, aqueous ammonia was added dropwise till the solution turn to clear. The temperature was raised to 60°C, and sodium dithionite (3.3g, 18.9mmol) was added in small portion until the color disappeared. The mixture was stirred for two additional hours in order to complete the reaction. Move out the solvent under reduced pressure distillation, washed the solid with cold water, and dried under high vacuum to obtain the corresponding product.
 

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