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Chemical Structure| 5131-66-8 Chemical Structure| 5131-66-8

Structure of 5131-66-8

Chemical Structure| 5131-66-8

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Product Details of [ 5131-66-8 ]

CAS No. :5131-66-8
Formula : C7H16O2
M.W : 132.20
SMILES Code : CC(O)COCCCC
English Name :1-Butoxypropan-2-ol
MDL No. :MFCD00021904
InChI Key :RWNUSVWFHDHRCJ-UHFFFAOYSA-N
Pubchem ID :21210

Safety of [ 5131-66-8 ]

Application In Synthesis of [ 5131-66-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 5131-66-8 ]

[ 5131-66-8 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 75-56-9 ]
  • [ 71-36-3 ]
  • [ 5131-66-8 ]
YieldReaction ConditionsOperation in experiment
38.5% With Al2O3/MgO composite at 120℃; Inert atmosphere;
With sodium hydroxide
With hematite at 160℃; for 8h; Autoclave;
With 1-ethyl-3-methyl-1H-imidazol-3-ium methylcarbonate at 50℃; for 0.166667h; Microwave irradiation; Green chemistry; 20 Example 20: The molar ratio of 1: 1: 0.001 of propylene oxide, butanol, and [EMIM] [MC] into microwave reaction tube uniformly mixed in a microwave reactor and heated to 50 , the reaction 10min.The mixture obtained by using the composition of the liquid phase mixture obtained by gas chromatography, the conversion was calculated 2.31% propylene oxide, propylene glycol monobutyl ether selectivity was 94.54%.
71 %Spectr. With 1-hydroxyethyl-3-methylimidazolium imidazolate at 30℃; for 24h; Green chemistry;

  • 2
  • [ 57-55-6 ]
  • [ 123-72-8 ]
  • [ 4352-99-2 ]
  • [ 15821-83-7 ]
  • [ 5131-66-8 ]
  • [ 71-36-3 ]
YieldReaction ConditionsOperation in experiment
1: 11.9 %Chromat. 2: 5.8 %Chromat. With hydrogen at 180℃; for 3h; Inert atmosphere; 14 n-Butyraldehyde (3.6 g, 4.5 ml; 0.05 mol), 1,2-propanediol (76.1 g, 73.4 ml; 1 mol), and 0.18 g of 10% Pd/C (5 wt % to n-butyraldehyde) are charged to a 150 ml Parr reactor. The system is purged with nitrogen three times. Then 500 psi of hydrogen is charged, the reactor is heated to 180° C., and the hydrogen pressure is adjusted to 1000 psi. After 3 hours at 180° C. and 1000 psi, GC analysis shows complete conversion of n-butyraldehyde and formation of an approximately 1:1 mixture of 2-butoxy-1-propanol and 1-butoxy-2-propanol (79.2%), n-butanol (5.8%), and cis/trans 2-propyl-4-methyl-1,3-dioxolane (11.9%).
5.8 %Chromat. With 10% Pd/C; hydrogen at 180℃; for 3h; 14 n-Butyraldehyde/1,2-Propanediol n-Butyraldehyde (3.6 g, 4.5 ml; 0.05 mol), 1,2-propanediol (76.1 g, 73.4 ml; 1 mol), and 0.18g of 10% Pd/C (5 wt% to n-butyraldehyde) are charged to a 150 ml Parr reactor. The system is purged with nitrogen three times. Then 3.5 MPa (500 psi) of hydrogen is charged, the reactor is heated to 180°C, and the hydrogen pressure is adjusted to 6.9 MPa (1000 psi). After 3 hours at 180°C and 6.9 MPa (1000 psi), GC analysis shows complete conversion of n-butyraldehyde and formation of an approximately 1:1 mixture of 2-butoxy-1-propanol and 1-butoxy-2-propanol (79.2%), n-butanol (5.8%), and cis/ trans 2-propyl-4-methyl-1,3-dioxolane (11.9%).
  • 3
  • [ 13520-78-0 ]
  • [ 5131-66-8 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
94% Stage #1: tungsten(VI) oxychloride; 1-butoxy-2-propanol at 20℃; for 1h; Stage #2: With ammonia at 20℃; 21 Examples 7 to 10: Preparation of [W(0)(OR)4] General procedure: The reactor was dried under vacuum at 60 °C for 1 hour. Heptane and the corresponding alcohols, glycol ether and polyglycol ether were dried over molecular sieve for several days according to standard methods. (0281) Under inert gas atmosphere 100 g tungsten(VI) chloride (252.15 mmol; 1.0 eq.) are dosed into a 1 L stirred reactor by a solid substances metering funnel. Subsequently, tungsten(VI) chloride is suspended and partly dissolved, respectively, in 500 ml_ heptane (anhydrous) and the reaction mixture is stirred at ambient temperature. 14.66 g acetone (252,15 mmol, (0282) 1.0 eq.) in 200 ml_ heptane are added over a period of about 1 h. The reaction mixture is stirred for 16 h at ambient temperature, whereby a bright orange reaction mixture is obtained. To the WOCI4 slurry stirred at about 20 °C the corresponding alcohol or glycol ether or polyglycol ether is added slowly over a period of about 1 h. During the addition of the corresponding alcohol or glycol ether or polyglycol ether the precipitate is slowly dissolved and the colour of the reaction mixture changes to yellow (sBuOH or glycol ether or polyglycol ether) or decolorates (/PrOH). Finally, a solution is obtained. After the addition of the corresponding alcohol or glycol ether or polyglycol ether the reactor is flushed with nitrogen gas for 5 min to remove hydrogen chloride having formed during the reaction. After flushing with nitrogen gas the reactor is connected to the pressure release valve and ammonia gas is passed into the reactor (500 mL/min; 0.55 bar). The reaction process is controlled via a mass flow controller. Supply of ammonia gas is finished as soon as the ammonia gas flow decreases to 0 ml_/ min. The pressure is released and the reactor is flushed purged with nitrogen gas to remove residual ammonia gas. Subsequently, the reaction mixture is filtered over a glass frit (D4). By a subsequent filtration over Celite colloidal solid residues are separated. Finally, the solvent is removed under reduced pressure (102 mbar, up to 60 °C) and the desired product [W(0)(OR)4] is obtained as solid or liquid.
 

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