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Type HazMat fee for 500 gram (Estimated)
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Chemical Structure| 5261-50-7 Chemical Structure| 5261-50-7

Structure of 5261-50-7

Chemical Structure| 5261-50-7

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Product Details of [ 5261-50-7 ]

CAS No. :5261-50-7
Formula : C12H11Cl
M.W : 190.67
SMILES Code : CC1=C2C=CC=CC2=C(CCl)C=C1
MDL No. :MFCD00079737

Safety of [ 5261-50-7 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314
Precautionary Statements:P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P321-P363-P405-P501
Class:8
UN#:1759
Packing Group:

Application In Synthesis of [ 5261-50-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 5261-50-7 ]

[ 5261-50-7 ] Synthesis Path-Downstream   1~3

  • 3
  • [ 57322-44-8 ]
  • [ 5261-50-7 ]
YieldReaction ConditionsOperation in experiment
With thionyl chloride; In dichloromethane; at 0 - 20℃;Inert atmosphere; General procedure: To a solution of arylmethanol (1.0 equiv) in CH2Cl2 (0.20 M) was added thionyl chloride (2.0equiv) at 0 C. After stirring the mixture at room temperature for several hours with monitoringreaction progress by TLC, the reaction was quenched with NaHCO3 aq. and extracted three times withCH2Cl2. The combined organic layer was dried over Na2SO4, filtrated, and concentrated in vacuo toafford S1. To a solution of S1 (1.0 equiv) in MeOH (0.2 M) was added trimethylamine in MeOH (3.2M, 1.2 equiv) at room temperture. After stirring the mixture at room temperature for several hourswith monitoring reaction progress by TLC, the mixture was concentrated in vacuo. The residue wastriturated in Et2O, and then filtrated to afford the corresponding benzyl ammonium 1.
 

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