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Chemical Structure| 53241-85-3 Chemical Structure| 53241-85-3

Structure of 53241-85-3

Chemical Structure| 53241-85-3

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Product Details of [ 53241-85-3 ]

CAS No. :53241-85-3
Formula : C10H8N2O4
M.W : 220.18
SMILES Code : O=C(C1=C(O)C2=NC(OC)=CC=C2N=C1)O

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Application In Synthesis of [ 53241-85-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 53241-85-3 ]

[ 53241-85-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 53241-85-3 ]
  • [ 249889-68-7 ]
YieldReaction ConditionsOperation in experiment
With trichlorophosphate; In quinoline; (d) 4-Chloro-6-methoxy-[1,5]naphthyridine Example 3 c (6.82 g) was heated in quinoline (20 ml) at reflux for 2 h, the mixture was cooled and poured into ether (200 ml) and the orange solid was filtered and washed with ether (5*200 ml). A sample (3.87 g) of the dried solid was treated with phosphorus oxychloride (30 ml) at room temp for 3 h, the solvent was removed in vacuo and the residue quenched with crushed ice (200 g) The mixture was basified with ammonia solution and filtered. The solid was washed with DCM (10*100 ml) and which were combined and evaporated. Flash chromatography (SiO2, DCM as eluent) gave the title compound as a yellow solid (3.00 g). m/z: 195,197 (MH+).
 

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