Home Cart 0 Sign in  

[ CAS No. 53242-76-5 ]

{[proInfo.proName]} ,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 53242-76-5
Chemical Structure| 53242-76-5
Structure of 53242-76-5 * Storage: {[proInfo.prStorage]}

Quality Control of [ 53242-76-5 ]

Related Doc. of [ 53242-76-5 ]

SDS
Alternatived Products of [ 53242-76-5 ]
Alternatived Products of [ 53242-76-5 ]

Product Details of [ 53242-76-5 ]

CAS No. :53242-76-5 MDL No. :MFCD07369702
Formula : C15H11ClO3 Boiling Point : 456.8°C at 760 mmHg
Linear Structure Formula :- InChI Key :-
M.W :274.70 g/mol Pubchem ID :104451
Synonyms :

Safety of [ 53242-76-5 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 53242-76-5 ]

  • Upstream synthesis route of [ 53242-76-5 ]
  • Downstream synthetic route of [ 53242-76-5 ]

[ 53242-76-5 ] Synthesis Path-Upstream   1~5

  • 1
  • [ 53242-76-5 ]
  • [ 53242-88-9 ]
Reference: [1] Archiv der Pharmazie, 1988, vol. 321, # 4, p. 205 - 208
  • 2
  • [ 1878-66-6 ]
  • [ 85-44-9 ]
  • [ 53242-76-5 ]
YieldReaction ConditionsOperation in experiment
80%
Stage #1: at 240 - 250℃; for 3 h;
Stage #2: With water; sodium hydroxide In water for 4 h; Reflux
Proportionion of p-chlorophenylacetic acid, phthalic anhydride and freshly melted sodium acetate in a reaction kettle,Rapidly heated to about 250 ° C,Stirring reaction at 240-250 ° C for 3 hours, the water produced during the reaction is discharged from the tail pipe;The reaction mixture is then placed in an open heat-resistant container while hot.Cool with stirring and add cold absolute ethanol.Heating to dissolve the solid as much as possible, cooling and filtering.Wash with absolute ethanol,filter,dry.The obtained solid is added to a solution of sodium hydroxide and water, stirred under reflux for 4 hours, cooled, diluted with water, acidified to pH 2-3 with 20percent hydrochloric acid, and stirred, cooled, and precipitated as a solid oil. , filtered, dried to obtain a crude product, the crude product was dissolved in acetone, the insoluble matter was filtered off, and acetone was evaporated.The residue was recrystallized from ethyl acetate.Get the product. MP 142-144 ° C, yield 80percent.
Reference: [1] Patent: CN108003005, 2018, A, . Location in patent: Paragraph 0010; 0011; 0012
  • 3
  • [ 20526-97-0 ]
  • [ 53242-76-5 ]
Reference: [1] Organic Letters, 2009, vol. 11, # 20, p. 4712 - 4715
  • 4
  • [ 105279-16-1 ]
  • [ 53242-76-5 ]
Reference: [1] Archiv der Pharmazie, 1988, vol. 321, # 4, p. 205 - 208
  • 5
  • [ 1878-66-6 ]
  • [ 53242-76-5 ]
Reference: [1] Archiv der Pharmazie, 1988, vol. 321, # 4, p. 205 - 208
Historical Records

Related Functional Groups of
[ 53242-76-5 ]

Chlorides

Chemical Structure| 85-56-3

[ 85-56-3 ]

2-(4-Chlorobenzoyl)benzoic acid

Similarity: 0.98

Chemical Structure| 7499-06-1

[ 7499-06-1 ]

5-Chloro-2-methylbenzoic acid

Similarity: 0.90

Chemical Structure| 5252-98-2

[ 5252-98-2 ]

4,5-Dichloro-2-methylbenzoic acid

Similarity: 0.87

Chemical Structure| 7099-88-9

[ 7099-88-9 ]

2-(4-Chlorophenyl)-2-oxoacetic acid

Similarity: 0.85

Chemical Structure| 74-11-3

[ 74-11-3 ]

4-Chlorobenzoic acid

Similarity: 0.84

Carboxylic Acids

Chemical Structure| 85-56-3

[ 85-56-3 ]

2-(4-Chlorobenzoyl)benzoic acid

Similarity: 0.98

Chemical Structure| 7499-06-1

[ 7499-06-1 ]

5-Chloro-2-methylbenzoic acid

Similarity: 0.90

Chemical Structure| 5252-98-2

[ 5252-98-2 ]

4,5-Dichloro-2-methylbenzoic acid

Similarity: 0.87

Chemical Structure| 7099-88-9

[ 7099-88-9 ]

2-(4-Chlorophenyl)-2-oxoacetic acid

Similarity: 0.85

Chemical Structure| 74-11-3

[ 74-11-3 ]

4-Chlorobenzoic acid

Similarity: 0.84

Aryls

Chemical Structure| 85-56-3

[ 85-56-3 ]

2-(4-Chlorobenzoyl)benzoic acid

Similarity: 0.98

Chemical Structure| 7499-06-1

[ 7499-06-1 ]

5-Chloro-2-methylbenzoic acid

Similarity: 0.90

Chemical Structure| 5252-98-2

[ 5252-98-2 ]

4,5-Dichloro-2-methylbenzoic acid

Similarity: 0.87

Chemical Structure| 7099-88-9

[ 7099-88-9 ]

2-(4-Chlorophenyl)-2-oxoacetic acid

Similarity: 0.85

Chemical Structure| 74-11-3

[ 74-11-3 ]

4-Chlorobenzoic acid

Similarity: 0.84

Ketones

Chemical Structure| 85-56-3

[ 85-56-3 ]

2-(4-Chlorobenzoyl)benzoic acid

Similarity: 0.98

Chemical Structure| 7099-88-9

[ 7099-88-9 ]

2-(4-Chlorophenyl)-2-oxoacetic acid

Similarity: 0.85

Chemical Structure| 118-04-7

[ 118-04-7 ]

2-(3-Amino-4-chlorobenzoyl)benzoic acid

Similarity: 0.78

Chemical Structure| 1889-71-0

[ 1889-71-0 ]

Benzyl 4-chlorophenyl ketone

Similarity: 0.78

Chemical Structure| 6332-83-8

[ 6332-83-8 ]

2-(4-Chlorophenyl)acetophenone

Similarity: 0.78