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Chemical Structure| 53517-65-0 Chemical Structure| 53517-65-0

Structure of 53517-65-0

Chemical Structure| 53517-65-0

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Product Details of [ 53517-65-0 ]

CAS No. :53517-65-0
Formula : C6H13NO3
M.W : 147.17
SMILES Code : N[C@@H](CO)C(OC(C)C)=O

Safety of [ 53517-65-0 ]

Application In Synthesis of [ 53517-65-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 53517-65-0 ]

[ 53517-65-0 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 7113-10-2 ]
  • [ 53517-65-0 ]
  • isopropyl (S)-3-(1H-imidazol-1-yl)-2-(2-phenylthiazole-4-carboxamido)propanoate [ No CAS ]
  • 2
  • [ 7113-10-2 ]
  • [ 53517-65-0 ]
  • C16H18N2O4S [ No CAS ]
YieldReaction ConditionsOperation in experiment
General procedure: EDCI (1.1 equiv.) and HOBt (1.1 equiv) were added to a solution of the intermediate acid compound 1a-j (1 equiv.) in anhydrous DMF. The reaction mixture was stirred for 1h at ambient temperature, and the L-serine ester (1.1 equiv.) and DIEA (3 equiv.) were added. The solution was heated to 70C for 6h and then cooled to room temperature. The reaction mixture was poured into ice water, and the resulting solid was filtered and dried to give the desired compound.
 

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