Alternatived Products of [ 53867-95-1 ]
Product Details of [ 53867-95-1 ]
CAS No. : | 53867-95-1 |
MDL No. : | MFCD09261104 |
Formula : |
C9H8N2O
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
160.17
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Pubchem ID : | - |
Synonyms : |
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Application In Synthesis of [ 53867-95-1 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 53867-95-1 ]
- 1
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[ 23432-46-4 ]
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[ 53867-95-1 ]
Yield | Reaction Conditions | Operation in experiment |
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With palladium on activated charcoal; ethanol Hydrogenation; |
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Yield | Reaction Conditions | Operation in experiment |
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IIf, konz. HCl (Ausb.:41.4percent); |
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4-Ethoxy-8-aminochinolin, HI; |
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- 3
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[ 53867-95-1 ]
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[ 4659-45-4 ]
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8-amino-4-(2,6-dichlorobenzoyloxy)quinoline
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
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With triethylamine In ethanol; ISOPROPYLAMIDE; water |
4.1 Example 4
(1) A mixture of 8-amino-4-hydroxyquinoline (300 mg), 2,6-dichlorobenzoyl chloride (432 mg), triethylamine (569 mg) and catalytic amount of dimethylaminopyridine in dimethylacetamide (3 ml) was stirred for 1 hour under ice-cooling. To the mixture was added water (3 ml) and the resulting precipitate was collected by filtration. The residue was suspended in hot ethanol (10 ml) with stirring. The resulting precipitate was collected by filtration, and the residue was purified by flash chromatography (ethyl acetate-dichloromethane) to give 8-amino-4-(2,6-dichlorobenzoyloxy)quinoline (240 mg). NMR (CDCl3, δ): 5.03 (2H, br s), 6.95 (1H, d, J=7.5 Hz), 7.30-7.52 (6H, m), 8.79 (1H, d, J=5 Hz) |