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Chemical Structure| 53931-59-2 Chemical Structure| 53931-59-2

Structure of 53931-59-2

Chemical Structure| 53931-59-2

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Product Details of [ 53931-59-2 ]

CAS No. :53931-59-2
Formula : C11H12O
M.W : 160.21
SMILES Code : C=CC(CCC1=CC=CC=C1)=O

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Application In Synthesis of [ 53931-59-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 53931-59-2 ]

[ 53931-59-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 53931-59-2 ]
  • [ 873-95-0 ]
  • 7,7-Dimethyl-2-phenethyl-7,8-dihydro-6H-quinolin-5-one hydrochloride [ No CAS ]
YieldReaction ConditionsOperation in experiment
45% 7,7-Dimethyl-2-phenethyl-7,8-dihydro-6H-quinolin-5-one hydrochloride A mixture of 4 A molecular sieves (140 mg), 5-phenylpent-1-en-3-one (Martin, R.; Romea, P.; Tey, C.; Urpi, F.; Vilarrasa, J.; SynLett. 1997, (12) 1414-1416.) (0.22 g, 1.4 mmol), <strong>[873-95-0]3-amino-5,5-dimethylcyclohex-2-en-1-one</strong>, and 10% Pd/C (14 mg) in toluene (4 ml) was heated at reflux for 4.5 h. It was filtered and the filtrate was evaporated under reduced pressure. The residue was purified by flash chromatography on silica gel (chloroform-methanol, 30:1), then it was treated by a dry HCl solution in diethyl ether to give the title compound (0.2 g, 45%) as a colorless solid. Physical characteristics are as follows Mp 173-175 C.; 1H NMR (CDCl3, TMS) δ: 1.18, 2.63, 3.24, 3.62, 3.70, 7.15-7.30, 7.37, and 8.61; Anal. Found (C19H21NO*HCl) (%): C, 71.6; H, 7.0; N, 4.4.
 

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