Alternatived Products of [ 54579-63-4 ]
Product Details of [ 54579-63-4 ]
CAS No. : | 54579-63-4 |
MDL No. : | MFCD09035494 |
Formula : |
C13H11NO3
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
229.23
|
Pubchem ID : | - |
Synonyms : |
|
Application In Synthesis of [ 54579-63-4 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 54579-63-4 ]
- 1
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[ 27237-21-4 ]
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[ 54579-63-4 ]
Yield | Reaction Conditions | Operation in experiment |
48% |
In methanol |
A11.
Synthesis of 4-(3-Carboxyphenoxy)aniline A slurry of 4-(3-carboxyphenoxy)-1-nitrobenzene (5.38 g, 20.7 mmol) and 10% Pd/C (0.50 g) in MeOH (120 mL) was stirred under an H2 atmosphere (balloon) for 2 d. The resulting mixture was filtered through a pad of Celite, then concentrated under reduced pressure to afford 4-(3-carboxyphenoxy)aniline as a brown solid (2.26 g, 48%): TLC (10% MeOH/90% CH2Cl2) Rf 0.44 (streaking). |
48% |
In methanol |
Synthesis of 4-(3-Carboxyphenoxy)aniline
Synthesis of 4-(3-Carboxyphenoxy)aniline A slurry of 4-(3-carboxyphenoxy)-1-nitrobenzene (5.38 g, 20.7 mmol) and 10% Pd/C (0.50 g) in MeOH (120 mL) was stirred under an H2 atmosphere (balloon) for 2 d. The resulting mixture was filtered through a pad of Celite, then concentrated under reduced pressure to afford 4-(3-carboxyphenoxy)aniline as a brown solid (2.26 g, 48%): TLC (10% MeOH/90% CH2Cl2) Rf 0.44 (streaking). |
48% |
In methanol |
11 Step 1.
A slurry of 4-(3-carboxyphenoxy)-1-nitrobenzene (5.38 g, 20.7 mmol) and 10% Pd/C (0.50 g) in MeOH (120 mL) was stirred under an H2 atmosphere (balloon) for 2 d. The resulting mixture was filtered through a pad of Celite, then concentrated under reduced pressure to afford 4-(3-carboxyphenoxy)aniline as a brown solid (2.26 g, 48%): TLC (10% MeOH/90% CH2Cl2) Rf 0.44 (streaking). |
48% |
With hydrogen In methanol for 48h; |
A.A11 Synthesis of 4-(3-Carboxyphenoxy)aniline.
Synthesis of 4-(3-Carboxyphenoxy)aniline. A slurry of 4-(3-carboxyphenoxy)-1-nitrobenzene (5.38 g, 20.7 mmol) and 10% Pd/C (0.50 g) in MeOH (120 mL) was stirred under an H2 atmosphere (balloon) for 2 d. The resulting mixture was filtered through a pad of Celite, then concentrated under reduced pressure to afford 4-(3-carboxyphenoxy)aniline as a brown solid (2.26 g, 48%): TLC (10% MeOH/90% CH2Cl2) Rf 0.44 (streaking). |
Reference:
[1]Current Patent Assignee: BAYER AG - US2003/144278, 2003, A1
[2]Current Patent Assignee: BAYER AG - US2001/11135, 2001, A1
[3]Current Patent Assignee: BAYER AG - US2002/165394, 2002, A1
Current Patent Assignee: BAYER AG - US2003/181442, 2003, A1
[4]Current Patent Assignee: BAYER AG - US2003/207872, 2003, A1
Location in patent: Page/Page column 13
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[ 212189-48-5 ]
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[ 54579-63-4 ]