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Chemical Structure| 54771-63-0 Chemical Structure| 54771-63-0

Structure of 54771-63-0

Chemical Structure| 54771-63-0

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Product Details of [ 54771-63-0 ]

CAS No. :54771-63-0
Formula : C7H12Cl2O
M.W : 183.08
SMILES Code : O=C(Cl)CCCCCCCl

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Application In Synthesis of [ 54771-63-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 54771-63-0 ]

[ 54771-63-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 54771-63-0 ]
  • [ 120068-37-3 ]
  • C19H14Cl2F6N4O2S [ No CAS ]
YieldReaction ConditionsOperation in experiment
(1) Take <strong>[120068-37-3]fipronil</strong> 10 mmol into a 100 mL flask,Then, 30 mL of tetrahydrofuran was added as a solvent, and magnetron stirring was added.Slowly add NaH in a batch of 20 mmol, with stirring,After the addition, continue stirring for 20 minutes, then add to it.10mmol (7-chloroheptanoic acid chloride, CAS: 54771-63-0)-0,Then, the mixture was heated under reflux at 80 C for 12 h. After the reaction was completed, the excess solvent was removed by rotary evaporation.Extract with 50 mL of ethyl acetate and 120 mL of saturated Na 2 CO 3 solution, and collect organic phase.Add 5g of silica gel to adsorb, spin dry and dry-load,Separation and purification by silica gel column chromatography using petroleum ether and ethyl acetate in a volume ratio of 4:11-(2,6-Dichloro-4-trifluoromethyl-phenyl)-5-(octacyclic imide-1-yl)-4-trifluoromethyl-1H-pyrazole-3-carbonitrile
 

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