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[ CAS No. 5554-54-1 ]

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Chemical Structure| 5554-54-1
Chemical Structure| 5554-54-1
Structure of 5554-54-1 * Storage: {[proInfo.prStorage]}

Quality Control of [ 5554-54-1 ]

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Alternatived Products of [ 5554-54-1 ]

Product Details of [ 5554-54-1 ]

CAS No. :5554-54-1 MDL No. :MFCD00234684
Formula : C10H19NO Boiling Point : 230-231°C at 760 mmHg
Linear Structure Formula :- InChI Key :-
M.W :169.26 g/mol Pubchem ID :-
Synonyms :

Safety of [ 5554-54-1 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 5554-54-1 ]

  • Downstream synthetic route of [ 5554-54-1 ]

[ 5554-54-1 ] Synthesis Path-Downstream   1~15

  • 1
  • [ 504-20-1 ]
  • [ 74-89-5 ]
  • [ 5554-54-1 ]
YieldReaction ConditionsOperation in experiment
With water
4 Proposed Preparation of 1,4-Dihydro-2,6-dimethyl-4-oxo-1-(1,2,2,6,6-Pentamethyl-4-piperidinyl-3-pyridinecarboxylic acid EXAMPLE 4 Proposed Preparation of 1,4-Dihydro-2,6-dimethyl-4-oxo-1-(1,2,2,6,6-Pentamethyl-4-piperidinyl-3-pyridinecarboxylic acid A sample of 1,2,2,6,6-pentamethyl-4-piperidone is prepared by known procedures from phorone and methyl amine.
4 Proposed Preparation of 1,4-Dihydro-2,6-dimethyl-4-oxo-1-(1,2,2,6,6-Pentamethyl-4-piperidinyl-3-pyridinecarboxylic acid Example 4 Proposed Preparation of 1,4-Dihydro-2,6-dimethyl-4-oxo-1-(1,2,2,6,6-Pentamethyl-4-piperidinyl-3-pyridinecarboxylic acid A sample of 1,2,2,6,6-pentamethyl-4-piperidone is prepared by known procedures from phorone and methyl amine.
  • 2
  • [ 5554-54-1 ]
  • [ 50-00-0 ]
  • [ 92884-76-9 ]
YieldReaction ConditionsOperation in experiment
85% With sodium hydroxide for 3h;
  • 3
  • [ 5554-54-1 ]
  • [ 917-54-4 ]
  • [ 75620-69-8 ]
YieldReaction ConditionsOperation in experiment
92% In diethyl ether at 20℃; for 4h;
Stage #1: 1,2,2,6,6-pentamethyl-4-piperidone; methyllithium In diethyl ether at 20℃; for 0.5h; Stage #2: With ammonium chloride In diethyl ether at 20℃; 62.1 To a stirred solution of 1,2,2, 6,6-pentamethylpiperidin-4-one(1.5 g, 8.88 mmol) in diethyl ether (25 mL) at rt was added MeLi (1.6 M, 5.5 mL, 8.88 mmol) slowly. The resulting mixture was stirred at rt for 30 min before it was quenched with sat. NH4C1 (15 mL). The mixture was then partitioned between EtOAc (35 mL) and sat. NaHC03 (25 mL). The organic layer was dried over Na2S04, filtered, and concentrated under reduced pressure to give crude 1,2,2,4,6,6- hexamethylpiperidin-4-ol (1.51 g) as an oil. LC-MS (ESI) m/z 186 (M + H)+.
  • 4
  • [ 5554-54-1 ]
  • [ 677-22-5 ]
  • 4-tert-butyl-4-hydroxy-1,2,2,6,6-pentamethylpiperidine [ No CAS ]
YieldReaction ConditionsOperation in experiment
75% In diethyl ether 1.) 5-10 deg C, 2.) RT, overnight, 3.) reflux, 5 h;
  • 5
  • [ 5554-54-1 ]
  • [ 74-88-4 ]
  • [ 113308-50-2 ]
YieldReaction ConditionsOperation in experiment
66% at 25℃; in the dark;
  • 6
  • [ 5554-54-1 ]
  • [ 20430-62-0 ]
YieldReaction ConditionsOperation in experiment
87% With sodium azide; sulfuric acid In chloroform dry ice/CH3OH then 6O deg C, 6 h;
  • 7
  • [ 5554-54-1 ]
  • [ 98-86-2 ]
  • 1-(2-hydroxy-2-phenylpropyl)-2,2,6,6-pentamethyl-4-piperidone [ No CAS ]
YieldReaction ConditionsOperation in experiment
15% In benzene Heating; UV irradiation;
  • 8
  • [ 5554-54-1 ]
  • [ 826-36-8 ]
YieldReaction ConditionsOperation in experiment
82% With water In acetone Heating; UV irradiation;
  • 9
  • [ 5554-54-1 ]
  • C24H29NO3 [ No CAS ]
  • C34H48N2O3 [ No CAS ]
YieldReaction ConditionsOperation in experiment
Stage #1: 1,2,2,6,6-pentamethyl-4-piperidone; C24H29NO3 With acetic acid In ISOPROPYLAMIDE at 20℃; for 0.25h; Stage #2: With sodium cyanoborohydride In ISOPROPYLAMIDE 61 Example 61 Synthesis Scheme EA suspension of 21 (20 mg, 0.053 mmol) and 1,2,2, 6,6-pentamethyl-4-piperidone in DMA (150 μL) and acetic acid (5 μL) is stirred for 15 min under an argon atmosphere at RT and combined with Na(OAc)3BH (34 mg, 0.16 mmol). After the reaction is complete, methanol is added, the solvents are eliminated in vacuo and the reaction mixture is purified by RP-chromatography (CH3CNiH2O, 5:95 to 95:5, 20 min, flow: 50 mL/min.).
  • 11
  • [ 5554-54-1 ]
  • [ 134614-22-5 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 2: 65 percent / Li, NH3(l) / 2-methyl-propan-2-ol; diethyl ether / 0.17 h / -50 °C 3: 96 percent / NaBH4 / ethanol; H2O / 12 h / 0 - 5 °C
Multi-step reaction with 2 steps 2: 96 percent / NaBH4 / ethanol; H2O / 12 h / 0 - 5 °C
Multi-step reaction with 3 steps 2: 1) Li, NH3(l) / 1) t-BuOH, ether, -50 deg C, 2) ether 3: 96 percent / NaBH4 / ethanol; H2O / 12 h / 0 - 5 °C
  • 12
  • [ 5554-54-1 ]
  • [ 134614-27-0 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 2: 65 percent / Li, NH3(l) / 2-methyl-propan-2-ol; diethyl ether / 0.17 h / -50 °C 3: 72 percent / diethyl ether / 4 h / 20 °C
Multi-step reaction with 3 steps 2: 1) Li, NH3(l) / 1) t-BuOH, ether, -50 deg C, 2) ether 3: 72 percent / diethyl ether / 4 h / 20 °C
  • 13
  • [ 5554-54-1 ]
  • [ 134614-23-6 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 2: 1) Li, NH3(l) / 1) t-BuOH, ether, -50 deg C, 2) ether 3: 95 percent / NaBH4 / ethanol; H2O / 12 h / 0 - 5 °C
  • 14
  • [ 5554-54-1 ]
  • [ 134614-28-1 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 2: 1) Li, NH3(l) / 1) t-BuOH, ether, -50 deg C, 2) ether 3: 65 percent / diethyl ether / 4 h / 20 °C
  • 15
  • [ 5554-54-1 ]
  • [ 504-20-1 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: 66 percent / 25 °C / in the dark 2: 55 percent / KOH / H2O / 1 h
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