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Chemical Structure| 561316-60-7 Chemical Structure| 561316-60-7

Structure of 561316-60-7

Chemical Structure| 561316-60-7

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Product Details of [ 561316-60-7 ]

CAS No. :561316-60-7
Formula : C9H9N5O2
M.W : 219.20
SMILES Code : O=C(N1C=CN=C1)NC2=NC(C)=CC(N2)=O

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Application In Synthesis of [ 561316-60-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 561316-60-7 ]

[ 561316-60-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 561316-60-7 ]
  • [ 160539-04-8 ]
  • 1-([2,2'-bipyridyl]-5-yl)-3-(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)urea [ No CAS ]
YieldReaction ConditionsOperation in experiment
48% With triethylamine; In N,N-dimethyl-formamide; at 70℃; Weigh N- (4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl) -1H-imidazole-1-carboxamide (0.085 g, 0.4 mmol, 1.2 eq)And [2,2'-bipyridyl] -5-amine (0.055g, 0.32mmol, 1eq) were added to the reaction flask, and nitrogen was pumped three times, and the reaction flask was addedN, N-dimethylformamide DMF (5mL)And triethylamine TEA (0.7 mL, 5.05 mmol, 15.8 equiv.), The clear solution was stirred at 70 C. overnight.The organic solvent was spin-dried, and the crude product was ultrasonically washed once with acetonitrile, suction filtered, and the obtained solid was ultrasonically washed with DCM / MeOH = 6/4, and filtered 2-3 times with suction.The product 1-([2,2'-bipyridyl] -5-yl) -3- (4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl) urea (2a), White solid powderYield: 50 mg (48%). Its structural formula is as follows:
  • 2
  • [ 160539-04-8 ]
  • [ 561316-60-7 ]
  • 1-([2,2'-bipyridyl]-5-yl)-3-(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)urea [ No CAS ]
 

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