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Chemical Structure| 56844-13-4 Chemical Structure| 56844-13-4

Structure of 56844-13-4

Chemical Structure| 56844-13-4

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Product Details of [ 56844-13-4 ]

CAS No. :56844-13-4
Formula : C6H2ClN3O2S
M.W : 215.62
SMILES Code : O=[N+](C1=CC2=C(Cl)N=CN=C2S1)[O-]
MDL No. :MFCD20265441

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Application In Synthesis of [ 56844-13-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 56844-13-4 ]

[ 56844-13-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 56844-13-4 ]
  • [ 2632-65-7 ]
  • C16H15N5O2S [ No CAS ]
YieldReaction ConditionsOperation in experiment
In isopropyl alcohol; at 80℃; for 2h; General procedure: To a solution of compound 5 (10 g, 0.046 mol) in i-PrOH (50 mL) was added 3-chloro-4-fluoroaniline (7.43 g, 0.051 mol) at room temperature. Subsequently, the mixture was heated to 80 C and stirred for 2 h. When the start material was consumed monitored by TLC, the reaction was cooled to room temperature. After removal of the solvent, the residue was suspended in ethyl acetate, filtered and washed with ethyl acetate to afford the intermediate 6,14.3 g as yellow solid in a 95% yield. ESI-MS m/z 325 [M+H]+.The other substituted anilines was treated with intermediate 5 for preparation of intermediates 6b-y according to the same procedure described for 6a.
 

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