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Chemical Structure| 569348-14-7 Chemical Structure| 569348-14-7

Structure of 569348-14-7

Chemical Structure| 569348-14-7

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Product Details of [ 569348-14-7 ]

CAS No. :569348-14-7
Formula : C14H18N2O3
M.W : 262.30
SMILES Code : O=C(N1CC(C(N)=O)CCC1)OCC2=CC=CC=C2
MDL No. :MFCD04115335
InChI Key :JVNTYSRHYYSZEM-UHFFFAOYSA-N
Pubchem ID :18526450

Safety of [ 569348-14-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 569348-14-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 569348-14-7 ]

[ 569348-14-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 78190-11-1 ]
  • [ 569348-14-7 ]
YieldReaction ConditionsOperation in experiment
2.7 g Step a. To a stirred solution of 1-((benzyloxy)carbonyl)pipendine-3-carboxylic acid (CAS Number 78190-1 1-1; 3.000 g, 11.390 mmol) in MeCN (20 ml) was added CDI (2.210 g, 13.670 mmol) at 0C.The reaction mixture was stirred at rt for 1 h. Ammonia solution (30% in water; 40 ml) was slowly added to the reaction mixture at rt and stirred for 16 h. The resulting mixture was diluted with water (50 ml), basified with saturated NaHCO3 solution and extracted with EtOAc (3 x 50m1). The combined organic phase was washed with aqueous citric acid solution (50 ml), dried over Na2SO4, filtered and concentrated on reduced pressure. The resulting residue was purified by flash columnchromatography (4% MeOH in DCM) yielding benzyl 3-carbamoylpipendine-1-carboxylate (2.700 g,10.30 mmol). LCMS: Method C, 1.585 mi MS: ES+ 263.39.
 

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