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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 56970-78-6 Chemical Structure| 56970-78-6
Chemical Structure| 56970-78-6

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Captopril EP Impurity D is an impurity of captopril, an orally active sulfhydryl-containing angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 0.025 μM.

Synonyms: 3-Bromoisobutyric acid

4.5 *For Research Use Only !

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Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

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Product Details of Captopril EP Impurity D

CAS No. :56970-78-6
Formula : C4H7BrO2
M.W : 167.00
SMILES Code : O=C(O)C(C)CBr
Synonyms :
3-Bromoisobutyric acid
MDL No. :MFCD01310530
InChI Key :BUPXDXGYFXDDAA-UHFFFAOYSA-N
Pubchem ID :304776

Safety of Captopril EP Impurity D

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H290-H302-H314-H332-H341
Precautionary Statements:P201-P260-P280-P305+P351+P338-P310
Class:8
UN#:3265
Packing Group:

Application In Synthesis of Captopril EP Impurity D

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 56970-78-6 ]

[ 56970-78-6 ] Synthesis Path-Upstream   1~2

  • 1
  • [ 79-41-4 ]
  • [ 56970-78-6 ]
References: [1] Bulletin of the Chemical Society of Japan, 1992, vol. 65, # 11, p. 3094 - 3102.
[2] Journal of Peptide Science, 2010, vol. 16, # 2, p. 91 - 97.
[3] Justus Liebigs Annalen der Chemie, 1880, vol. 200, p. 68.
[4] , 1944, # 35, p. 15[5] Chem.Abstr., 1945, p. 2488.
[6] Journal of Pharmaceutical Sciences, 1984, vol. 73, # 12, p. 1843 - 1844.
[7] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 2000, # 1, p. 71 - 78.
[8] Tetrahedron Letters, 2014, vol. 55, # 12, p. 2015 - 2018.
[9] Letters in Organic Chemistry, 2015, vol. 12, # 3, p. 217 - 221.
  • 2
  • [ 20609-71-6 ]
  • [ 56970-78-6 ]
References: [1] Tetrahedron, 1993, vol. 49, # 18, p. 3691 - 3734.
 

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