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Chemical Structure| 57105-65-4 Chemical Structure| 57105-65-4

Structure of 57105-65-4

Chemical Structure| 57105-65-4

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Product Details of [ 57105-65-4 ]

CAS No. :57105-65-4
Formula : C10H9ClN2O
M.W : 208.65
SMILES Code : O=C(NCC#C)NC1=CC=C(Cl)C=C1
MDL No. :MFCD01676519

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Application In Synthesis of [ 57105-65-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 57105-65-4 ]

[ 57105-65-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 57105-65-4 ]
  • [ 25625-57-4 ]
  • 2-{4-[3-(4-chlorophenyl)ureidomethyl][1,3]triazol-1-yl}-N-(3-trifluoromethylphenyl)acetamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
79% With sodium azide; copper(II) sulfate; sodium L-ascorbate; In water; N,N-dimethyl-formamide; at 40℃; General procedure: Urea linked alkynes 2(a-c) (1.0 mmol), 2-bromo-N-phenylacetamides3(a-f) (1.0 mmol) were dissolved in dimethylformamide(4 mL) in a round bottom flask. Sodium azide (3.0 mmol) in water (2 mL) copper sulphate (0.02 mmol) in water (2 mL) wereadded to the reaction mixture followed by addition of sodiumascorbate (0.02 mmol) and the mixture was stirred at 40 C for2e3 h. After completion of the reaction, reaction mixture wasfiltered and the solid obtained was washed with ice cold water andsmall amount of ethyl acetate to yield triazole hybrids 4(a-r).
 

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