Home Cart Sign in  
Chemical Structure| 582-17-2 Chemical Structure| 582-17-2
Chemical Structure| 582-17-2

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of 2,7-Dihydroxynaphthalene

CAS No. :582-17-2
Formula : C10H8O2
M.W : 160.17
SMILES Code : OC1=CC2=CC(O)=CC=C2C=C1
MDL No. :MFCD00004085
InChI Key :DFQICHCWIIJABH-UHFFFAOYSA-N
Pubchem ID :11397

Safety of 2,7-Dihydroxynaphthalene

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of 2,7-Dihydroxynaphthalene

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 582-17-2 ]

[ 582-17-2 ] Synthesis Path-Downstream   1~6

  • 1
  • [ 582-17-2 ]
  • [ 118591-58-5 ]
  • 7-[2-(2-Hydroxy-ethoxy)-ethoxy]-naphthalen-2-ol [ No CAS ]
  • [ 185246-94-0 ]
  • 2
  • [ 1310-58-3 ]
  • [ 582-17-2 ]
  • [ 50594-82-6 ]
  • [ 67-68-5 ]
  • [ 7757-82-6 ]
  • [ 122452-28-2 ]
YieldReaction ConditionsOperation in experiment
In Petroleum ether; EXAMPLE (II-1) STR36 12.5 g (0.05 mol) of 3,4,5-trichloro-benzotrifluoride are added slowly to a stirred mixture, heated to 60 C., of 8.0 g (0.05 mol) of 2,7-dihydroxy-naphthalene, 4.2 g (0.075 mol) of potassium hydroxide powder and 100 ml of dimethyl sulphoxide, and stirring of the reaction mixture is continued for approximately 3 hours at 60 C. After the mixture has cooled to approximately 20 C., it is diluted with water and methylene chloride and filtered. The organic phase is separated from the filtrate, washed with water, dried using sodium sulphate and filtered. The solvent is distilled off from the filtrate under a waterpump vacuum, the residue is stirred with petroleum ether, and the product which is obtained in this process in the form of crystals is isolated by filtering off with suction. 4.9 g (26% of theory) of 7-(2,6-dichloro-4-trifluoromethyl-phenoxy)-2-naphthol of melting point 98 C. are obtained.
  • 3
  • [ 582-17-2 ]
  • [ 50594-82-6 ]
  • [ 67-68-5 ]
  • [ 7757-82-6 ]
  • [ 122452-28-2 ]
YieldReaction ConditionsOperation in experiment
With potassium hydroxide; In Petroleum ether; STR73 12.5 g (0.05 mol) of 3,4,5-trichloro-benzotrifluoride are added slowly and with stirring to a mixture of 8.0 g (0.05 mol) of 2,7-dihydroxynaphthalene, 4.2 g (0.075 mol) of pulverulent potassium hydroxide and 100 ml of dimethyl sulphoxide, which has been warmed to 60 C., and the reaction mixture is then stirred for a further approx. 3 hours at 60 C. After the mixture has been cooled to approximately 20 C., it is diluted with water and methylene chloride, and filtered. The organic phase is separated off from the filtrate, washed with water, dried using sodium sulphate and filtered. The solvent is removed from the filtrate by distillation in a water-pump vacuum, the residue is stirred with petroleum ether and the product which is thus obtained in the form of crystals is isolated by filtering with suction. 4.9 g (26% of theory) of 7-(2,6-dichloro-4-trifluoromethylphenoxy)-2-naphthol of melting point 98 C. are obtained. In analogy to Example (II-1) the starting substances of the formula (II) listed below in Table 2 may be prepared. STR74
  • 5
  • [ 582-17-2 ]
  • [ 118591-58-5 ]
  • [ 185246-94-0 ]
  • 6
  • [ 2631-77-8 ]
  • [ 582-17-2 ]
  • C27H16I2O4 [ No CAS ]
YieldReaction ConditionsOperation in experiment
20% With methanesulfonic acid; at 90℃; for 5h; General procedure: In a container (internal capacity: 1 L) equipped with a stirrer, a condenser tube, and a burette, 24 g (150 mmol) of 2,7-dihydroxynaphthalene (a reagent manufactured by Sigma-Aldrich), 25.4 g (71 mmol) of <strong>[2631-77-8]3,5-diiodosalicylaldehyde</strong> (a reagent manufactured by Tokyo Chemical Industry Co., Ltd.), and 200 mL of 1-methoxy-2-propanol were charged, and 1.3 g (14 mmol) of methanesulfonic acid (a reagent manufactured by Kanto Chemical Co., Inc.) was added to prepare a reaction solution. This reaction solution was stirred at 90 C. for 5 hours and allowed to react. After the reaction finished, 1.7 L of pure water was added to the reaction solution, extraction with ethyl acetate was performed, followed by concentration, to obtain a solution. The obtained solution was separated and purified by column chromatography to obtain 9.2 g of the objective compound (X-27N35IB) represented by the following formula (purity: 98.7% and yield: 20%). As a result of measuring the molecular weight of the obtained compound (X-27N35IB) by the above method, it was 658. Also, since the following peaks were found by performing the 1H-NMR measurement under the above measurement conditions, the compound was confirmed to have a chemical structure of the following formula (X-27N35IB). 1H-NMR (d6-DMSO): δ (ppm) 10.4 (1H, -OH), 9.8 (1H, -OH), 9.5 (1H, -OH), 6.7-8.0 (12H, Ph), 6.2 (1H, Methine)
 

Historical Records

Technical Information

Categories