0
Home Cart 0 Sign in  

[ CAS No. 59105-50-9 ]

{[proInfo.proName]} ,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
2D
Chemical Structure| 59105-50-9
Chemical Structure| 59105-50-9
Structure of 59105-50-9 *Storage: {[proInfo.prStorage]}

Quality Control of [ 59105-50-9 ]

Related Doc. of [ 59105-50-9 ]

SDS

Product Details of [ 59105-50-9 ]

CAS No. :59105-50-9MDL No. :MFCD00452964
Formula : C12H8BrNO Boiling Point : -
Linear Structure Formula :-InChI Key :-
M.W :262.10Pubchem ID :796643
Synonyms :

Computed Properties of [ 59105-50-9 ]

TPSA : 30 H-Bond Acceptor Count : 2
XLogP3 : - H-Bond Donor Count : 0
SP3 : 0.00 Rotatable Bond Count : 2

Safety of [ 59105-50-9 ]

Signal Word:WarningClassN/A
Precautionary Statements:P280-P305+P351+P338UN#:N/A
Hazard Statements:H302Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 59105-50-9 ]

  • Upstream synthesis route of [ 59105-50-9 ]
  • Downstream synthetic route of [ 59105-50-9 ]

[ 59105-50-9 ] Synthesis Path-Upstream   1~4

  • 1
  • [ 100-58-3 ]
  • [ 183608-47-1 ]
  • [ 59105-50-9 ]
YieldReaction ConditionsOperation in experiment
61% at -20 - 20℃; for 5.00 h; Inert atmosphere The gas protection Ar, the step a 5-bromo-N-methyl-N-methoxy-nicotinamide (400 mg, 1 . 63mmol) dissolving THF (10 ml), cooled to -20 °C, is dripped slowly into the phenyl magnesium bromide THF solution of (1M, 4.9 ml), is omitted, -20 ° C reaction 1h, slowly to room temperature reaction 4hSaturated NaHC03 aqueous solution was quenched, the THF was distilled off, and the mixture was extracted with ethyl acetate Dried over Na2SO4, filtered, the solvent evaporated, and the residue was chromatographed on a latex gel (260 mg, 61percent).
Reference: [1] Patent: CN103626693, 2016, B. Location in patent: Paragraph 0220-0222
  • 2
  • [ 591-51-5 ]
  • [ 183608-47-1 ]
  • [ 59105-50-9 ]
Reference: [1] Patent: EP1661904, 2006, A1. Location in patent: Page/Page column 47
  • 3
  • [ 20826-04-4 ]
  • [ 59105-50-9 ]
Reference: [1] Patent: CN103626693, 2016, B
  • 4
  • [ 39620-02-5 ]
  • [ 71-43-2 ]
  • [ 59105-50-9 ]
Reference: [1] Pharmaceutical Chemistry Journal, 2001, vol. 35, # 7, p. 349 - 352
Historical Records

Related Functional Groups of
[ 59105-50-9 ]

Bromides

Chemical Structure| 38940-62-4

[ 38940-62-4 ]

3-Acetyl-5-bromopyridine

Similarity: 0.90

Chemical Structure| 1256823-89-8

[ 1256823-89-8 ]

1-(5-Bromo-2-methylpyridin-3-yl)ethanone

Similarity: 0.87

Chemical Structure| 100397-96-4

[ 100397-96-4 ]

1-(4-Bromophenyl)-2-(pyridin-4-yl)ethanone

Similarity: 0.80

Chemical Structure| 1883347-28-1

[ 1883347-28-1 ]

1-(5-Bromopyridin-3-yl)-2,2,2-trifluoroethanone hydrochloride

Similarity: 0.75

Chemical Structure| 27012-25-5

[ 27012-25-5 ]

5-Bromo-2-phenylpyridine

Similarity: 0.74

Aryls

Chemical Structure| 5424-19-1

[ 5424-19-1 ]

Phenyl(pyridin-3-yl)methanone

Similarity: 0.81

Chemical Structure| 100397-96-4

[ 100397-96-4 ]

1-(4-Bromophenyl)-2-(pyridin-4-yl)ethanone

Similarity: 0.80

Chemical Structure| 40061-21-0

[ 40061-21-0 ]

1-(Pyridin-3-yl)-2-(p-tolyl)ethanone

Similarity: 0.78

Chemical Structure| 27012-25-5

[ 27012-25-5 ]

5-Bromo-2-phenylpyridine

Similarity: 0.74

Chemical Structure| 100866-13-5

[ 100866-13-5 ]

2-(Pyridin-4-yl)-1-(p-tolyl)ethanone

Similarity: 0.70

Ketones

Chemical Structure| 38940-62-4

[ 38940-62-4 ]

3-Acetyl-5-bromopyridine

Similarity: 0.90

Chemical Structure| 1256823-89-8

[ 1256823-89-8 ]

1-(5-Bromo-2-methylpyridin-3-yl)ethanone

Similarity: 0.87

Chemical Structure| 5424-19-1

[ 5424-19-1 ]

Phenyl(pyridin-3-yl)methanone

Similarity: 0.81

Chemical Structure| 100397-96-4

[ 100397-96-4 ]

1-(4-Bromophenyl)-2-(pyridin-4-yl)ethanone

Similarity: 0.80

Chemical Structure| 40061-21-0

[ 40061-21-0 ]

1-(Pyridin-3-yl)-2-(p-tolyl)ethanone

Similarity: 0.78

Related Parent Nucleus of
[ 59105-50-9 ]

Pyridines

Chemical Structure| 38940-62-4

[ 38940-62-4 ]

3-Acetyl-5-bromopyridine

Similarity: 0.90

Chemical Structure| 1256823-89-8

[ 1256823-89-8 ]

1-(5-Bromo-2-methylpyridin-3-yl)ethanone

Similarity: 0.87

Chemical Structure| 5424-19-1

[ 5424-19-1 ]

Phenyl(pyridin-3-yl)methanone

Similarity: 0.81

Chemical Structure| 100397-96-4

[ 100397-96-4 ]

1-(4-Bromophenyl)-2-(pyridin-4-yl)ethanone

Similarity: 0.80

Chemical Structure| 40061-21-0

[ 40061-21-0 ]

1-(Pyridin-3-yl)-2-(p-tolyl)ethanone

Similarity: 0.78