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Chemical Structure| 5943-04-4 Chemical Structure| 5943-04-4

Structure of 5943-04-4

Chemical Structure| 5943-04-4

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Product Details of [ 5943-04-4 ]

CAS No. :5943-04-4
Formula : C7H6Cl2O2S
M.W : 225.09
SMILES Code : O=S(C1=CC=C(Cl)C=C1)(CCl)=O
MDL No. :MFCD00032558

Safety of [ 5943-04-4 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H312-H315-H318-H332-H335
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P330-P332+P313-P362-P403+P233-P405-P501
Class:8
UN#:3261
Packing Group:

Application In Synthesis of [ 5943-04-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 5943-04-4 ]

[ 5943-04-4 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 5943-04-4 ]
  • [ 16155-03-6 ]
  • [ 1253422-21-7 ]
  • 2
  • [ 14752-66-0 ]
  • [ 2156-56-1 ]
  • [ 5943-04-4 ]
YieldReaction ConditionsOperation in experiment
74% In water; at 90.0℃; for 7.0h; To the solution of salt 3 (3.97 g, 20 mmol) in water(20mL) <strong>[2156-56-1]sodium dichloroacetate</strong> (3.77 g, 2.5 mmol) was added. The mixture was stirred andheated at 90Cfor 7 hours, kipping pH ~7, by dropping 30% solution of natrium hydroxide. Aftercooling to the room temperature the precipitate was filtered off, washed bywarm water and dried. The product 7 waspurified by recrystallization from ethanol. Chloromethyl-4-chlorophenyl sulfone8 was obtained in 74% yield. M.p. = 120-121C. IR (cm-1):2970 (CHaliph.), 1600 (CHar), 1320, 1140 (SO2).1H-NMR, 400MHz, (CDCl3) delta: 4.53 (s, 2H);7.58-7.60 (m, 2H); 7.90- 7.92 (m. 2H). 13C NMR (100 MHz, CDCl3) delta: 65.99; 124.03;127.47; 132.49; 146.27. Elemental analysis: for C7H6Cl2O2S(225.09) Calcd.: 37.35 % C, 2.69 %H. Found: 37.33 % C, 2.72 % H.
 

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