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Chemical Structure| 60148-63-2 Chemical Structure| 60148-63-2

Structure of 60148-63-2

Chemical Structure| 60148-63-2

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Product Details of [ 60148-63-2 ]

CAS No. :60148-63-2
Formula : C15H14O2
M.W : 226.27
SMILES Code : C=CC(C1=CC=CC(OC2=CC=CC=C2)=C1)O

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Application In Synthesis of [ 60148-63-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 60148-63-2 ]

[ 60148-63-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 2012-74-0 ]
  • [ 60148-63-2 ]
  • (1RS,2RS)-1-(3-phenoxyphenyl)allyl 2-(4-chlorophenyl)-3-methylbutanoate [ No CAS ]
  • (1SR,2RS)-1-(3-phenoxyphenyl)allyl 2-(4-chlorophenyl)-3-methylbutanoate [ No CAS ]
YieldReaction ConditionsOperation in experiment
In 30mL two-neck flask, 2-(4-chlorophenyl) 3-methylbutanoic acid (3a) (purchased from Tokyo Chemical Industry) (0.149 g, 0.70 mmol), toluene (5.8 mL), placed in thionyl chloride (3.5 mL) and refluxed at 125 C. for 1 hour. The reaction solution was concentrated under reduced pressure, the alcohol compound (5a) (0.078g, 0.350mmol), toluene (4.6mL), N,N-dimethyl-4-aminopyridine (DMAP) (0.420g, 3.44mmol), triethylamine (0.148 g , 1.47 mmol) in a 30 mL two-necked flask, and the mixture was stirred at room temperature for 17 hours. After completion of the reaction was confirmed by thin layer chromatography, the reaction mixture was extracted with toluene and dried over anhydrous sodium sulfate. The solvent was concentrated in vacuo, and the resulting compound was purified by silica gel column chromatography (mobile phase: hexane: ethyl acetate = 100: 1) to give to give pyrethroid compound (1a) as a yellow liquid (0.132 g, yield: 90%).
 

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