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Chemical Structure| 6023-70-7 Chemical Structure| 6023-70-7

Structure of 6023-70-7

Chemical Structure| 6023-70-7

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Product Details of [ 6023-70-7 ]

CAS No. :6023-70-7
Formula : C11H11N3O2
M.W : 217.22
SMILES Code : CC(CC(NC1=CC2=C(NN=C2)C=C1)=O)=O
MDL No. :MFCD04067172

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Application In Synthesis of [ 6023-70-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 6023-70-7 ]

[ 6023-70-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 3240-35-5 ]
  • [ 2033-24-1 ]
  • [ 6023-70-7 ]
  • 4-[4-(aminosulfonyl)phenyl]-N-1H-indazol-5-yl-2-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
8% With ammonium acetate; acetic acid; for 3h;Heating / reflux; Example 43.; 4- [4- (Aminosulfonyl) phenyl]-N-lH-indazol-5-yl-2-methyl-6-oxo- 1, 4,5, 6-tetrahydro-3-pyridinecarboxamide;4-Formylbenzenesulfonamide (200 mg, 1.07 mmol, 1.00 equiv), 2,2-dimethyl- 1, 3-dioxane-4,6-dione (155 mg, 1-07 mmol, 1.00 equiv), N-lH-indazol-5-yl-3- oxobutanamidemethyl (233 mg, 1-07 mmol, 1.00 equiv), and ammonium acetate (87 mg, 1.13 mmol, 1.05 equiv) were dissolved in acetic acid (1.0 mL) and heated to reflux for 3 hours, then cooled to room temperature. The reaction was quenched with solid K2CO3 and then diluted slowly with water (lOmL) and EtOAc (10 mL). The phases were separated, and the organic phase was washed once with satd. NaCl. The organic phase was dried over Na2S04, filtered, and concentrated en vacuo. The residue was triturated with EtOAc and CH2C12, filtered, and washed with EtOAc, Et2O, and CH2C12 to provide 37 mg (8%) of the title compound as an off white solid. MS (ES+) m/e 426 [M+H] +
  • 2
  • [ 3240-35-5 ]
  • [ 6023-70-7 ]
  • [ 22265-37-8 ]
  • 4-[4-(aminosulfonyl)phenyl]-N-1H-indazol-5-yl-6-methyl-2-[4-(methyloxy)phenyl]-1,4-dihydro-5-pyrimidinecarboxamide [ No CAS ]
 

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