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Chemical Structure| 60399-02-2 Chemical Structure| 60399-02-2

Structure of 60399-02-2

Chemical Structure| 60399-02-2

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Product Details of [ 60399-02-2 ]

CAS No. :60399-02-2
Formula : C8H11NO
M.W : 137.18
SMILES Code : OC1=CC=CC=C1CNC
MDL No. :MFCD09043889

Safety of [ 60399-02-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Application In Synthesis of [ 60399-02-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 60399-02-2 ]

[ 60399-02-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 67-56-1 ]
  • [ 60399-02-2 ]
  • [ 5635-98-3 ]
YieldReaction ConditionsOperation in experiment
85% With potassium hydrogencarbonate; 1,4-dichlorobutane; for 24.0h;Reflux; In a 100 mL three-necked flask equipped with a condenser and a thermometer, 4.1 g (30 mmol) of 2-[(methylamino)methyl]phenol was added.Potassium hydrogencarbonate 3.0g (30mmol),1,4-dichlorobutane 4.19 g (33 mmol) and 60 mL of methanol,The mixture was heated to reflux with stirring and allowed to react for 24 hours.The TLC monitoring showed that the reaction was completed. The reaction mixture was concentrated, and then 100 mL of dichloromethane and 30 mL of 1M diluted hydrochloric acid solution were added, and the mixture was stirred for 20 minutes, and liquid was separated.The methylene chloride phase was dried over anhydrous sodium sulfate, filtered, and the filtrate was concentrated, and then filtered.The target product was obtained in an amount of 3.52 g, yield: 85%.
 

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