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Chemical Structure| 60889-32-9 Chemical Structure| 60889-32-9

Structure of 60889-32-9

Chemical Structure| 60889-32-9

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Product Details of [ 60889-32-9 ]

CAS No. :60889-32-9
Formula : C6H11NO
M.W : 113.16
SMILES Code : C12CNCC1COC2
MDL No. :MFCD14581351
InChI Key :HQQVXVKQOPZRBJ-UHFFFAOYSA-N
Pubchem ID :21421150

Safety of [ 60889-32-9 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314-H226
Precautionary Statements:P501-P270-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P303+P361+P353-P301+P330+P331-P363-P301+P312+P330-P304+P340+P310-P305+P351+P338+P310-P403+P235-P405
Class:8(3)
UN#:2920
Packing Group:

Application In Synthesis of [ 60889-32-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 60889-32-9 ]

[ 60889-32-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 90176-80-0 ]
  • [ 60889-32-9 ]
  • 4-(tetrahydro-1H-furo[3,4-c]pyrrol-5(3H)-yl)-2-(trifluoromethyl)benzaldehyde [ No CAS ]
YieldReaction ConditionsOperation in experiment
54% With caesium carbonate; In N,N-dimethyl-formamide; at 100℃; j00335J A round-bottom flask was charged with hexahydro-1H-furo[3,4-c]pyrrole (1.18 g, 10.4 mmol, 2.00 equiv), <strong>[90176-80-0]4-fluoro-2-(trifluoromethyl)benzaldehyde</strong> (1.00 g, 5.21 mmol, 1.00 equiv), cesium carbonate (3.40 g, 10.4 mmol, 2.00 equiv), and DMF (10 mL). The reaction mixture was stirred overnight at 100 C and quenched with water (20 mL). The resulting solution was extracted with EtOAc (3 x 50 mL) and the organic layers were combined, washed with brine (1 x 50 mL), dried over Na2 SO4, filtered and concentrated under reduced pressure. The residue was chromatographed on a silica gel to provide 0.800 g (54% yield) of 4-(tetrahydro-1H-furo[3,4- c]pyrrol -5 (3H)-yl)-2-(trifluoromethyl)benzaldehyde as a yellow oil. LCMS (ESI, m/z): 286 [M+H].
  • 2
  • [ 90176-80-0 ]
  • [ 60889-32-9 ]
  • N-(1-(4-(4-(tetrahydro-1H-furo[3,4-c]pyrrol-5(3H)-yl)-2-(trifluoromethyl)benzyl)piperazine-1-carbonyl)-1H-pyrazol-3-yl)acetamide [ No CAS ]
 

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