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Chemical Structure| 61357-67-3 Chemical Structure| 61357-67-3

Structure of 61357-67-3

Chemical Structure| 61357-67-3

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Product Details of [ 61357-67-3 ]

CAS No. :61357-67-3
Formula : C14H8O2
M.W : 208.21
SMILES Code : O=C(C=CC1=CC2=C3)C=C1C=C2C=CC3=O
MDL No. :N/A

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Application In Synthesis of [ 61357-67-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 61357-67-3 ]

[ 61357-67-3 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 61357-67-3 ]
  • [ 13361-34-7 ]
  • C36H42N2O4 [ No CAS ]
YieldReaction ConditionsOperation in experiment
With ammonium acetate; acetic acid; In toluene; at 100 - 115℃; for 30h;Dean-Stark; Inert atmosphere; 2,6-Anthraquinone (2 gm, 9.5 mmol) and toluene (40 mL) are mixed in a clean 250 mL 2 neck round bottom flask equipped with Dean-Stark condenser and nitrogen inlet. 2- (0229) Ethylhexyl cyanoacetate (4.4 gm, 22.3 mmol), ammonium acetate (153 mg, 2.0 mmol), and acetic acid (2.8 mL) are added sequentially at 25-30C. The reaction mixture is refluxed for approximately 18 hours at 100-1 l5C. The water is periodically removed from Dean-Stark condenser during the reaction. The reaction is monitored by TLC (ethyl acetate/hexane). After the complete consumption of 2,6-anthraquinone by TLC, the reaction mixture is refluxed for another 12 hours and then cooled to room temperature. The toluene layer is washed with water (2x25 mL) followed by saturated sodium bicarbonate solution (25 mL) and again with water (25 mL). The organic layer is evaporated under reduced pressure at 45-50C to obtain crude product as pale brown semisolid. The crude product is purified by column chromatography by eluting with ethyl acetate in hexane to afford pure product.
  • 2
  • [ 61357-67-3 ]
  • [ 13361-34-7 ]
  • C25H25NO3 [ No CAS ]
YieldReaction ConditionsOperation in experiment
With ammonium acetate; acetic acid; In toluene; at 100 - 115℃; for 18h;Dean-Stark; Inert atmosphere; 2,6-Anthracenedione (6 gm, 28.5 mmol) and toluene (40 mL) are mixed in a clean 250 mL 2 neck round bottom flask equipped with Dean-Stark condenser and nitrogen inlet. 2-Ethylhexyl cyanoacetate (4.4 gm, 22.3 mmol), ammonium acetate (153 mg, 2.0 mmol), and acetic acid (2.8 mL) are added sequentially at 25-30C. The reaction mixture is refluxed for approximately 18 hours at 100-1 l5C. The water is periodically removed from Dean-Stark condenser during the reaction. The reaction is monitored by TLC (ethyl acetate/hexane). After the complete consumption of 2,6-anthracenedioneby TLC, the reaction mixture is cooled to room temperature. The toluene layer is washed with water (2x25 mL) followed by saturated sodium bicarbonate solution (25 mL) and again with water (25 mL). The organic layer is evaporated under reduced pressure at 45-50C to obtain crude product as pale brown semisolid. The crude product is purified by column chromatography by eluting with ethyl acetate in hexane to afford pure product.
 

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