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Chemical Structure| 61703-39-7 Chemical Structure| 61703-39-7

Structure of 61703-39-7

Chemical Structure| 61703-39-7

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Product Details of [ 61703-39-7 ]

CAS No. :61703-39-7
Formula : C14H18N2O3
M.W : 262.30
SMILES Code : O=C(N1[C@H](C(N)=O)CCCC1)OCC2=CC=CC=C2
MDL No. :MFCD09261346

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Application In Synthesis of [ 61703-39-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 61703-39-7 ]

[ 61703-39-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 28697-11-2 ]
  • [ 61703-39-7 ]
YieldReaction ConditionsOperation in experiment
Step 1: Benzyl (2S)-2-(aminocarbonyl)piperidine-l-carboxylate (WWl) A mixture of (2S)-l-[(benzyloxy)carbonyl]hexahydro-2-pyridinecarboxylic acid (1 eq), TBTU (1.3 eq), DIPEA (1.3 eq), in DMF (2 M) was stirred at R.T. for 30 min then ammonia in dioxane (4 M, 3 eq) was added and stirring was continued for 2h. The reaction mixture was diluted with EtOAc, washed sequentially with sat. aq. NaHCO3 solution and brine. The solution was dried (Na2SO4), filtered and concentrated under reduced pressure. The crude was purified by crystallization from Et2O giving a white solid. MS (ES) Ci4HisN2O3 required: 262, found: 263 (M+H)+.
 

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