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Chemical Structure| 62827-73-0 Chemical Structure| 62827-73-0

Structure of 62827-73-0

Chemical Structure| 62827-73-0

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Product Details of [ 62827-73-0 ]

CAS No. :62827-73-0
Formula : C16H12O2
M.W : 236.27
SMILES Code : O=C1C2=CC=CC=C2C=C(C3=CC=C(C)C=C3)O1

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Application In Synthesis of [ 62827-73-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 62827-73-0 ]

[ 62827-73-0 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 720-94-5 ]
  • [ 88284-48-4 ]
  • [ 62827-73-0 ]
  • 1-trifluoromethyl-3-(p-tolyl)-1H-isochromen-1-ol [ No CAS ]
  • 2-(trifluoroacetyl)-2'-(p-toluoyl)diphenylmethane [ No CAS ]
YieldReaction ConditionsOperation in experiment
26.1 mg; 8.4 mg; 8.7 mg With cesium fluoride; In acetonitrile; at 20℃; for 16h; General procedure: To a solution of 4,4,4-trifluoro-1-phenylbutan-1,3-dione (108 mg, 0.50 mmol) and CsF (228 mg, 1.50 mmol) in acetonitrile (7 mL) was added triflate 1a (253 mg, 0.85 mmol) in acetonitrile (3 mL). After refluxing for 6h, the reaction mixture was washed with water, dried over MgSO4, filtered, and evaporated to give pale yellow oil, which was chromatographed over silica gel by elution with hexane-dichloromethane (1:1) to afford 3-phenylisocoumarin 3b (71.1 mg, 0.32 mmol).
  • 2
  • [ 720-94-5 ]
  • [ 88284-48-4 ]
  • [ 62827-73-0 ]
  • 2-(trifluoroacetyl)-2'-(p-toluoyl)diphenylmethane [ No CAS ]
YieldReaction ConditionsOperation in experiment
51.5 mg; 17.5 mg With cesium fluoride; In acetonitrile; for 5h;Reflux; General procedure: To a solution of 4,4,4-trifluoro-1-phenylbutan-1,3-dione (108 mg, 0.50 mmol) and CsF (228 mg, 1.50 mmol) in acetonitrile (7 mL) was added triflate 1a (253 mg, 0.85 mmol) in acetonitrile (3 mL). After refluxing for 6h, the reaction mixture was washed with water, dried over MgSO4, filtered, and evaporated to give pale yellow oil, which was chromatographed over silica gel by elution with hexane-dichloromethane (1:1) to afford 3-phenylisocoumarin 3b (71.1 mg, 0.32 mmol).
  • 3
  • [ 720-94-5 ]
  • [ 88284-48-4 ]
  • [ 62827-73-0 ]
 

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