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Chemical Structure| 6317-35-7 Chemical Structure| 6317-35-7

Structure of 6317-35-7

Chemical Structure| 6317-35-7

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Product Details of [ 6317-35-7 ]

CAS No. :6317-35-7
Formula : C9H17NO2
M.W : 171.24
SMILES Code : O=C(OCC)CCN1CCCC1
MDL No. :MFCD00020861
InChI Key :MVPICKVDHDWCJQ-UHFFFAOYSA-N
Pubchem ID :80590

Safety of [ 6317-35-7 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H315-H318-H335
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P330-P332+P313-P362-P403+P233-P405-P501
Class:8
UN#:2735
Packing Group:

Application In Synthesis of [ 6317-35-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 6317-35-7 ]

[ 6317-35-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 35247-24-6 ]
  • [ 6317-35-7 ]
  • [ 65651-80-1 ]
YieldReaction ConditionsOperation in experiment
17%Spectr.; 64%Spectr. With bis(triphenylphosphine)carbonyliridium(I) chloride; 1,1,3,3-Tetramethyldisiloxane; In toluene; at 20℃; for 1h;Inert atmosphere; General procedure: To a solution of IrCl(CO)(PPh3)2 (1.0 mol %) and a b-amido ester11 or 15 (0.5 mmol) in toluene (5 mL) was added TMDS (1.0 mmol)at rt under an argon atmosphere. The reaction mixture was stirredfor 1 h at the same temperature. The resulting mixture wasconcentrated under reduced pressure. The residue was puried byash chromatography on silica gel to afford the corresponding b-enamino ester.4.2.1. Ethyl (E)-3-(pyrrolidin-1-yl)acrylate (12a)Flash chromatography on silica gel (eluent: EtOAc/n-Hex-ane 1:3) to give the known compound 12a [18a] as a yellow oil(81 mg, yield: 96%);1H NMR (400 MHz, CDCl3) d 1.20 (t, J 7.2 Hz,3H), 1.89 (br s, 4H), 3.21 (br s, 4H), 4.06 (q, J 7.2 Hz, 2H), 4.45 (d,J 12.8 Hz, 1H), 7.59 (d, J 12.8 Hz, 1H) ppm;13C NMR (100 MHz,CDCl3) d 14.5, 25.1, 48.8 (br w), 51.8 (br w), 58.6, 84.5, 148.5,169.5 ppm; IR (lm) n: 2975, 2868, 1687, 1612, 1365, 1305, 1241,1185, 1141, 1095, 1047, 784 cm1; HRMS calcd for [C9H15NO2Na](M Na): 192.0995; found: 192.0989.
 

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