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Chemical Structure| 63270-87-1 Chemical Structure| 63270-87-1

Structure of 63270-87-1

Chemical Structure| 63270-87-1

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Product Details of [ 63270-87-1 ]

CAS No. :63270-87-1
Formula : C9H17NO
M.W : 155.24
SMILES Code : O=CC=CN(CCC)CCC

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Application In Synthesis of [ 63270-87-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 63270-87-1 ]

[ 63270-87-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 63270-87-1 ]
  • [ 120069-21-8 ]
  • C14H24N2O2S [ No CAS ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; at 60℃;Sonication; In a 500 mL three-necked flask equipped with a thermometer,First, 69 mL (0.5 mol) of 3-bis (n-propyl) aminoacrolein and 5.0 g of K2CO3 were added, followed by adding 73.6 g (0.5 mol) of isopropyl cyanoethyl sulfone,well mixed,The prepared reactor into the ultrasonic instrument, set the ultrasonic radiation conditions,At a temperature of 60 C,Ultrasonic power of 300W and the frequency of 100KHz reaction conditions,TLC (petroleum ether: dichloromethane 1: 2 developed, sublimation of iodine color) 3-bis (n-propyl) amino acrolein reaction was complete, cooled to 20 C, HCl gas was introduced,The conditions of ultrasonic irradiation were the same as above, the reaction temperature was 20 C,After about 50 min of reaction, HPLC traces the reaction until the reaction is complete. Then after the reaction, sodium carbonate solution was added to adjust pH = 7-8,The organic phase was washed with 10 mL of deionized water and then separated. The organic layer was dried over molecular sieves overnight, filtered, the solvent removed by heating and evaporation to give 2-chloro-3- Isopropylsulfonylpyridine, 101.3 g of a colorless liquid in a yield of 92.2%.
 

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