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Chemical Structure| 633697-56-0 Chemical Structure| 633697-56-0

Structure of 633697-56-0

Chemical Structure| 633697-56-0

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Product Details of [ 633697-56-0 ]

CAS No. :633697-56-0
Formula : C8H8F3NO2S
M.W : 239.22
SMILES Code : O=S(C1=CC=CC=C1C(F)(F)F)(NC)=O
MDL No. :MFCD05270097

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Application In Synthesis of [ 633697-56-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 633697-56-0 ]

[ 633697-56-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 67-56-1 ]
  • [ 1869-24-5 ]
  • [ 633697-56-0 ]
YieldReaction ConditionsOperation in experiment
85% With [(Cp*IrCl)2(4,4',6,6'-tetrahydroxy-2,2'-bipyrimidine)][Cl]2; potassium hydroxide; In water; at 130℃; for 12h; Combine <strong>[1869-24-5]o-trifluoromethylbenzenesulfonamide</strong> (112.6 mg, 0.5 mmol), iridium catalyst (5.1 mg, 0.005 mmol, 1 mol%), potassium hydroxide (28 mg, 0.5 mmol, 1 equiv), and methanol (0.3 mL), water (0.9 mL) was sequentially added to the reaction vessel. After the reaction mixture was reacted at 130 C for 12 hours in a reaction vessel, it was cooled to room temperature. The solvent was removed by rotary evaporation, and then the purified target compound was obtained by column chromatography (developing solvent: petroleum ether / ethyl acetate), yield: 85%.
 

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