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Chemical Structure| 648423-80-7 Chemical Structure| 648423-80-7

Structure of 648423-80-7

Chemical Structure| 648423-80-7

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Product Details of [ 648423-80-7 ]

CAS No. :648423-80-7
Formula : C12H9N3
M.W : 195.22
SMILES Code : N#CC1=CC2=CN=C(C3CC3)N=C2C=C1
MDL No. :MFCD22690187

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Application In Synthesis of [ 648423-80-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 648423-80-7 ]

[ 648423-80-7 ] Synthesis Path-Downstream   1~1

  • 1
  • cyclopropane carboxyimidamide hydrochloride [ No CAS ]
  • [ 146137-79-3 ]
  • [ 648423-80-7 ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; In acetonitrile; for 144h;Molecular sieve; Heating / reflux; Into 60 ml of acetonitrile were suspended 1.5 g of <strong>[146137-79-3]4-fluoro-3-formylbenzonitrile</strong>, 2.0 g of potassium carbonate, 2.3 g of molecular sieves 4A, and 1.7 g of cyclopropanecarboxyimidamide hydrochloride, followed by 6 days of heating under refluxing. Insoluble matter was separated by filtration and the filtrate was concentrated. The residue was subjected to silica gel column chromatography to obtain 220 mg of the title compound from an eluate eluted with hexane-ethyl acetate (8:2, v/v). FABMASS 196 [M+H]+
 

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