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[ CAS No. 651341-54-7 ]

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Chemical Structure| 651341-54-7
Chemical Structure| 651341-54-7
Structure of 651341-54-7 * Storage: {[proInfo.prStorage]}

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Product Details of [ 651341-54-7 ]

CAS No. :651341-54-7 MDL No. :MFCD16621731
Formula : C6H13NO Boiling Point : -
Linear Structure Formula :- InChI Key :-
M.W :115.17 g/mol Pubchem ID :7176280
Synonyms :

Safety of [ 651341-54-7 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 651341-54-7 ]

  • Downstream synthetic route of [ 651341-54-7 ]

[ 651341-54-7 ] Synthesis Path-Downstream   1~2

  • 2
  • [ 651341-54-7 ]
  • 2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)-2-phenylpropanoic acid [ No CAS ]
  • 2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)-1-((R)-3-methoxypiperidin-1-yl)-2-phenylpropan-1-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
25% With N-ethyl-N,N-diisopropylamine; HATU; In tetrahydrofuran; at 20.0℃; for 15.0h; To a stirred solution of 2- (5-amino-2- (furan-2-yl) -7H-pyrazolo [4, 3-e] [1, 2, 4] triazolo [1, 5-c] pyrimidin-7-yl) -2-phenylpropanoic acid (50 mg, 0.13 mmol) , HATU (54 mg, 0.14 mmol) and DIEA (50 mg, 0.39 mmol) in THF (15 ml) was added (R) -3-methoxypiperidine (15 mg, 0.13 mmol) . The reaction mixture was stirred at rt for 15h. After completion, the reaction mixture was diluted with EA (30 ml) and then washed with H2O (15 ml X 2) . The organic layer was dried over Na2SO4, filtered and then concentrated under reduced pressure to afford a residue. The residue was purified by prep-TLC with PE: EA (1: 5) to afford the product (15.6 mg, 25%) .1H NMR (400 MHz, DMSO-d6) delta 8.27 (s, 1H) , 8.07 (s, 2H) , 7.96 (s, 1H) , 7.38-7.12 (m, 6H) , 6.74 (dd, J = 4Hz, 2Hz, 1H) , 4.28-3.86 (m, 1H) , 3.28 (s, 3H) , 3.26-3.08 (m, 2H) , 2.85-2.70 (m, 2H) , 2.36-2.16 (m, 4H) , 1.73-1.59 (m, 1H) , 1.31-1.03 (m, 2H) ppm. MS: M/e 487 (M+1)+.
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