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Chemical Structure| 65235-90-7 Chemical Structure| 65235-90-7

Structure of 65235-90-7

Chemical Structure| 65235-90-7

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Product Details of [ 65235-90-7 ]

CAS No. :65235-90-7
Formula : C10H7NO2S
M.W : 205.23
SMILES Code : O=C1C=C(O)N=C(C2=CC=CC=C2)S1
MDL No. :MFCD00793775

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Application In Synthesis of [ 65235-90-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 65235-90-7 ]

[ 65235-90-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 65235-90-7 ]
  • [ 42059-80-3 ]
  • [ 1263273-26-2 ]
YieldReaction ConditionsOperation in experiment
52% With pyridine; In tetrahydrofuran; at 50 - 60℃; for 2h; 2-Aryl-4-hydroxy-6H-1,3-thiazin-6-one 7 (0.01 mol) was dissolved in 20 ml of THF, then 1 ml of pyridine was added. The solution was heated to 50 C and the respective 3-formylchromone 1 was added (0.011 mol). Heating was continued at 50-60 C for 2 h with intermittent stirring. The solvent was removed in vacuo (20 mmHg), EtOH (10 ml) was added to the residue, and the formed precipitate filtered, washed with EtOH (3 × 10 ml), and recrystallized from THF to give pyranochromenes 11 as brownish-orange powder. The ethanolic rinses were evaporated under a current of air to a volume of 5 ml. CH2Cl2 (20 ml) was added, the formed precipitate filtered, washed with CH2Cl2 (3 × 10 ml), and recrystallized from EtOH to give propenoic acids 13 as yellowish powders. The CH2Cl2 rinses were evaporated under a current of air to a volume of 5 ml and n-hexane (20 ml) was added. The formed precipitate was filtered, washed with n-hexane (3 × 10 ml), and recrystallized from CH2Cl2-C6H14 (1:1) to give pyranothiazines 12 as yellow powders.
 

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