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Chemical Structure| 6555-30-2 Chemical Structure| 6555-30-2

Structure of 6555-30-2

Chemical Structure| 6555-30-2

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Product Details of [ 6555-30-2 ]

CAS No. :6555-30-2
Formula : C11H14O3
M.W : 194.23
SMILES Code : CC(C1=CC=C(OC)C=C1)CC(O)=O
MDL No. :MFCD02671263

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Application In Synthesis of [ 6555-30-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 6555-30-2 ]

[ 6555-30-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 580-15-4 ]
  • [ 6555-30-2 ]
  • C20H20N2O2 [ No CAS ]
YieldReaction ConditionsOperation in experiment
45.5% With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20℃; 4. To a solution of Compound 4 (400 mg, 2 mmol) in DCM (10 mL) were added 6- aminoquinoline (300 mg, 2 mmol), EDCI (760 mg, 4 mmol) and DMAP (80 mg). The reaction mixture was stirred at RT overnight. TLC indicated reaction completion. The residue was treated with water and extracted with DCM. The organic extracts were washed with brine, dried over anhydrous Na2SO4, filtered and concentrated to give a crude oil. The crude product was purified by silica gel chromatography to afford Example 10 (300 mg, 45.5 %). 1HNMR (CDCI3, 300 MHz) δ: 8.9-8.8 (s, 1 H), 8.3-8.2 (s, 1 H), 8.2-8.1 (m, 1 H), 8.1-7.9 (d, 1 H), 7.6-7.5 (m, 1 H), 7.4-7.2 (m, 7 H), 7.1-7.0 (s, 1 H), 6.9-6.8 (d, 2 H), 3.9-3.8 (s, 3 H), 3.5-3.4 (m, 1 H), 2.7-2.6 (m, 2 H), 1.5-1.3 (m, 3 H). LC-MS: m/z= 321(M+1) +.
 

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