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Chemical Structure| 65764-56-9 Chemical Structure| 65764-56-9

Structure of 65764-56-9

Chemical Structure| 65764-56-9

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Product Details of [ 65764-56-9 ]

CAS No. :65764-56-9
Formula : C13H13NO2
M.W : 215.25
SMILES Code : O=C(C1=CC=CC2=C1NC3=C2CCCC3)O
MDL No. :MFCD00458334

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* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 65764-56-9 ]

[ 65764-56-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 108-94-1 ]
  • [ 33906-30-8 ]
  • [ 65764-56-9 ]
YieldReaction ConditionsOperation in experiment
76% In acetic acid; for 3.5h;Heating / reflux; A solution of 2-hydrazinobenzoic acid, hydrochloride (40.0 g, 0.212 mol) and cyclohexanone (26 ml, 0.254 mol) in ACOH (500 ml) was refluxed for 3.5 h before the solvent was evaporated and water (200 ml) and EtOAc (1000 ml) was added. Organic layer was extracted with 1N NAOH and the combined aqueous layers acidified with 6 N HCl and extracted with EtOAc, organic layers dried (MGS04) and concentrated. Yield 34.88 g (76%); white solid. 'H NMR (400 MHz, DMSO-d6) 8 1.77-1. 80 (M, 4 H), 2.61-2. 64 (M, 2 H), 2.75 (M, 2 H), 7.01 (t, J=8 Hz, 1 H), 7.58 (d, J=8 Hz, 1 H), 7.63 (d, J=8 Hz, 1 H), 10.56 (s, 1 H), 12.81 (s, 1 H). I3C NMR (100 MHz, DMSO-d6) 8 20.39, 22.70, 22.87, 108.46, 112.51, 117.50, 122. 28, 122.64, 128.82, 134.73, 136.26, 168.10. CAS [65764-56-9]
 

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