Home Cart Sign in  
Chemical Structure| 667936-71-2 Chemical Structure| 667936-71-2

Structure of 667936-71-2

Chemical Structure| 667936-71-2

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 667936-71-2 ]

CAS No. :667936-71-2
Formula : C18H18F2O2
M.W : 304.33
SMILES Code : O=C(O)CCCCC(C1=CC=C(F)C=C1)C2=CC=C(F)C=C2
MDL No. :MFCD20484287

Safety of [ 667936-71-2 ]

Application In Synthesis of [ 667936-71-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 667936-71-2 ]

[ 667936-71-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 667936-71-2 ]
  • [ 146394-99-2 ]
  • [ 905301-61-3 ]
YieldReaction ConditionsOperation in experiment
70% With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;dmap; In dichloromethane; at 20℃; To a solution of <strong>[146394-99-2](4-amino-but-2-enyl)-carbamic acid tert-butyl ester</strong> (1.Og, 5.36mmol) in dry CH2Cl2 (40 ml) was added 6,6-bis-(4-fluorophenyl)-hexanoic acid (1.62g, 5.36mmol) under nitrogen. To the reaction was added EDC (2.04g, 10.72mmol) and DMAP (cat) and the reaction mixture stirred under nitrogen at room temperature overnight. The reaction was then concentrated under reduced pressure. The residue dissolved in ethyl acetate: water (10:1) (150ml). The organic was washed with water (30ml, 2x) and 10% NaOH (30 ml) and dried over MgSO4 and evaporated to dryness. The resulting residue was purified by column chromatography using CH2C12:CH3OH (15:1) to give the desired product in 70% yield.
 

Historical Records

Technical Information

Categories