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Chemical Structure| 67436-17-3 Chemical Structure| 67436-17-3

Structure of 67436-17-3

Chemical Structure| 67436-17-3

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Product Details of [ 67436-17-3 ]

CAS No. :67436-17-3
Formula : C15H19NO6
M.W : 309.31
SMILES Code : O=C(OC)[C@@H](NC(OCC1=CC=CC=C1)=O)CCC(OC)=O
MDL No. :MFCD20271472

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Application In Synthesis of [ 67436-17-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 67436-17-3 ]

[ 67436-17-3 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 5672-83-3 ]
  • [ 67436-17-3 ]
  • [ 75266-40-9 ]
  • 2
  • [ 13907-82-9 ]
  • [ 67436-17-3 ]
  • [ 5672-83-3 ]
  • [ 75857-94-2 ]
  • 3
  • [ 13907-82-9 ]
  • [ 75-05-8 ]
  • [ 67436-17-3 ]
  • [ 5672-83-3 ]
  • N-((2S,3S,4R,5R,6R)-4,5-Bis-benzyloxy-6-benzyloxymethyl-2-butyl-tetrahydro-pyran-3-yl)-acetamide [ No CAS ]
  • 4
  • [ 67436-17-3 ]
  • [ 478646-28-5 ]
YieldReaction ConditionsOperation in experiment
90.8% With sodium tetrahydroborate; ethanol; In tetrahydrofuran; at 0 - 15℃; In a dropping funnel,Thermometer dry four bottles,150 g of a compound of formula V (eta = 2) was added,And 150 g of tetrahydrofuran,Stirring dissolved after cooling to 0 ~ l0 C,29 g of sodium borohydride was added,Further, 72 g of anhydrous ethanol was added,Insulation in the 10 ~ 15 C reaction to the raw material reaction is complete by adding 90g acetic acid,The pH of the reaction solution was adjusted to 4 to 5, and 330 g of water and 350 g of ethyl acetate were added thereto,The organic phase was washed with a sodium carbonate solution,Washed with a saturated saline solution,After treatment with anhydrous sodium sulfate,filter,Concentration (-0. IMPa, below 45 C),A solid was obtained which was beaten with 102 g of n-heptane,filter,Dried to give 111.5 g of a compound of formula IV as a white solid,The yield was 90.8%Chemical purity 96. 3%Optical purity 99. 8%.
 

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