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[ CAS No. 67765-42-8 ]

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Cat. No.: {[proInfo.prAm]}
2D
Chemical Structure| 67765-42-8
Chemical Structure| 67765-42-8
Structure of 67765-42-8 *Storage: {[proInfo.prStorage]}

Quality Control of [ 67765-42-8 ]

Purity: {[proInfo.showProBatch.pb_purity]}

Related Doc. of [ 67765-42-8 ]

SDS

Product Details of [ 67765-42-8 ]

CAS No. :67765-42-8MDL No. :MFCD11046419
Formula :C9H7NO4Boiling Point :-
Linear Structure Formula :-InChI Key :N/A
M.W :193.16Pubchem ID :10750295
Synonyms :

Computed Properties of [ 67765-42-8 ]

TPSA : - H-Bond Acceptor Count : -
XLogP3 : - H-Bond Donor Count : -
SP3 : - Rotatable Bond Count : -

Safety of [ 67765-42-8 ]

Signal Word:WarningClassN/A
Precautionary Statements:P261-P305 P351 P338UN#:N/A
Hazard Statements:H302-H315-H319-H335Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 67765-42-8 ]

  • Downstream synthetic route of [ 67765-42-8 ]

[ 67765-42-8 ] Synthesis Path-Downstream   1~10

  • 1
  • [ 67765-42-8 ]
  • [ 74-88-4 ]
  • [ 91105-97-4 ]
YieldReaction ConditionsOperation in experiment
53% 6-Methoxyisanoic anhydride (3.86 g, 20 mmol) was added to DMF (60 mL) and NaH (960 mg, 40 mmol) was added at 0 C. After stirring at room temperature for 30 minutes, iodomethane (1.85 mL,30 mmol) was added at room temperature for 12 hours. The reaction was poured into ice water, the solid was precipitated, filtered and dried to give an off-white solid (2.2 g, 53%).
8.37 parts (80.7%) In N,N-dimethyl-formamide; (b) To a stirred and cooled (<10 C.) solution of 9.65 parts of [67765-42-8]5-methoxy-2H-3,1-benzoxazine-2,4(1H)-dione in 54 parts of N,N-dimethylformamide were added portionwise 2.64 parts of a sodium hydride dispersion 50%. After stirring for 1 hour in an ice bath. 7.81 parts of iodomethane were added dropwise at <15 C. When the reaction mixture was solidified, 45 parts of N,N-dimethylformamide were added and a sodium hydride dispersion 50% was further added dropwise. Upon complete addition, stirring was continued overnight while the reaction mixture was allowed to reach room temperature. The reaction mixture was poured into ice water and 2,2'-oxybispropane was added. The precipitated product was filtered off, washed with water and dried, yielding 8.37 parts (80.7%) of 5-methoxy-1-methyl-2H-3,1-benzoxazine-2,4(1H)-dione; mp. 215.8 C. (interm. 2)
  • 2
  • [ 4427-96-7 ]
  • [ 67765-42-8 ]
  • syn-1,10-dimethoxy-6,15-divinyl-6,7,15,16-tetrahydrodibenzo[e,l][1,8,4,11]dioxadiazacyclotetradecine-9,18(5H,14H)-dione [ No CAS ]
  • anti-1,10-dimethoxy-6,15-divinyl-6,7,15,16-tetrahydrodibenzo[e,l][1,8,4,11]dioxadiazacyclotetradecine-9,18(5H,14H)-dione [ No CAS ]
  • 3
  • [ 67765-42-8 ]
  • 3-(3-((4,5-dihydrothiazol-2-yl)thio)propyl)-5-methoxybenzo[d][1,2,3]triazin-4(3H)-one [ No CAS ]
  • 5
  • [ 67765-42-8 ]
  • C14H19N5O2 [ No CAS ]
  • 6
  • [ 67765-42-8 ]
  • 5-methoxy-3-(2-(4-(2-nitrobenzoyl)piperazin-1-yl)ethyl)benzo[d][1,2,3]triazin-4(3H)-one [ No CAS ]
  • 7
  • [ 67765-42-8 ]
  • [ 1591-38-4 ]
YieldReaction ConditionsOperation in experiment
With ammonium carbonate; In 1,4-dioxane; at 60℃; for 8h; General procedure: A suspension of isatoic anhydride (35 mmol), ammonium carbonate (140 mmol), and 1,4-dioxane (150 mL) was heated at 60 C. After stirring for 8 h, the reaction mixture was cooled to room temperature and evaporated underreduced pressure, and then water (200 mL) was added to the residue, which was extracted with DCM (80 mL × 3). The organic layerwas dried over anhydrous Na2SO4, and concentrated to give compound 3 in yield of 84%.
With ammonium carbonate; In 1,4-dioxane; at 60℃; for 8h; General procedure: A suspension of substituted isatoic anhydride (35 mmol), ammonium carbonate (140 mmol), and 1,4-dioxane (150 mL) was heated at 60 C. After stirring for 8 h, the reaction mixture was cooled to room temperature and evaporated under reduced pressure, and then water (200 mL) was added to the residue, which was extracted with CH2Cl2 (380 mL). The organic layer was dried over anhydrous Na2SO4 and concentrated to give compounds 9 in yields of 63-94%.
  • 9
  • [ 67765-42-8 ]
  • C10H10BrN3O2 [ No CAS ]
  • 10
  • [ 14963-96-3 ]
  • [ 34954-65-9 ]
  • [ 67765-42-8 ]
Historical Records

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Related Parent Nucleus of
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