Alternatived Products of [ 67952-38-9 ]
Product Details of [ 67952-38-9 ]
CAS No. : | 67952-38-9 |
MDL No. : | MFCD08442945 |
Formula : |
C11H16O2
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | UOACSUDCGMMDFW-UHFFFAOYSA-N |
M.W : |
180.24
|
Pubchem ID : | 101151 |
Synonyms : |
|
Application In Synthesis of [ 67952-38-9 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 67952-38-9 ]
- 1
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[ 104-20-1 ]
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[ 67952-38-9 ]
Yield | Reaction Conditions | Operation in experiment |
89% |
With Poly(n-butyl-4-vinylpyridinium)borohydride; In ethanol; at 20℃; for 4.4h; |
General procedure: To a solution of the substrate (1 mmol) in ethanol as asolvent (5 mL) in a round-bottomed flask (25 mL) equippedwith a magnetic stirrer, P(BVP)BH4 (100 mg) was addedand stirred at room temperature. The progress of thereaction was monitored by TLC. On completion of thereaction, the mixture was filtered and the used reagent waswashed successively with HCl (1.0 M, 2 10 mL) andethanol (2 5 mL). The combined filtrates were evaporatedand the pure product was obtained in moderate to excellent yields. In a few cases in which the reaction wasnot complete, the crude product was purified on silica gelwith an appropriate eluent (Scheme 1). |
|
With sodium tetrahydroborate; |
General procedure: rac-3a and rac-4a were produced by reducing <strong>[104-20-1]4-(4'-methoxyphenyl)-2-butanone</strong> and 1-phenyl-2-butanone, respectively, with NaBH4 as reported [4]. NMR data for were consistent (rac)-3a and (rac)-4a were consistent those reported [3]. |
Reference:
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[3]Tetrahedron Letters,2001,vol. 42,p. 2137 - 2139
[4]Comptes Rendus Chimie,2014,vol. 17,p. 23 - 29
[5]Organic and Biomolecular Chemistry,2019,vol. 17,p. 1749 - 1753
[6]Comptes Rendus Chimie,2013,vol. 16,p. 721 - 727
[7]Annales de Chimie (Cachan, France),1925,vol. <10> 4,p. 423,435
[8]Tetrahedron Letters,1999,vol. 40,p. 1417 - 1418
[9]Journal of the Chemical Society. Perkin Transactions 1 (2001),2001,p. 2526 - 2531
[10]Journal of Organic Chemistry,2007,vol. 72,p. 30 - 34
[11]Journal of Organic Chemistry,2010,vol. 75,p. 2981 - 2988
[12]Journal of Molecular Catalysis B: Enzymatic,2015,vol. 115,p. 155 - 159
[13]Journal of the American Chemical Society,2016,vol. 138,p. 6139 - 6142
[14]Journal of the American Chemical Society,2016,vol. 138,p. 7520 - 7523
[15]RSC Advances,2016,vol. 6,p. 96616 - 96622
[16]Organic Letters,2017,vol. 19,p. 4413 - 4415
[17]European Journal of Organic Chemistry,2018,vol. 2018,p. 798 - 805
- 2
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[ 104-21-2 ]
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[ 67952-38-9 ]