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Chemical Structure| 67952-60-7 Chemical Structure| 67952-60-7

Structure of 67952-60-7

Chemical Structure| 67952-60-7

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Product Details of [ 67952-60-7 ]

CAS No. :67952-60-7
Formula : C5H10OS2
M.W : 150.26
SMILES Code : CC(C)(SSC)C=O
MDL No. :MFCD00142943

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Application In Synthesis of [ 67952-60-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 67952-60-7 ]

[ 67952-60-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 67952-60-7 ]
  • [ 71176-54-0 ]
  • (5-(2-methyl-2-(methyldisulfanyl)propylamino)-1,3-phenylene)dimethanol [ No CAS ]
YieldReaction ConditionsOperation in experiment
65% <strong>[71176-54-0](5-amino-1,3-phenylene)dimethanol</strong> (2.5 g, 16.32 mmol) and 2-(methyldithio)isobutyraldehyde (2.347 ml, 16.32 mmol) were stirred at ambient temperature in absolute ethanol (82 ml) until completely dissolved (3 hours). The mixture was cooled to 0° C. in an ice bath and sodium borohydride (0.741 g, 19.59 mmol) was added. The reaction was stirred for 1 hour at 0° C., and was then quenched slowly with cold 5percent HCl solution. The mixture was diluted with dichloromethane and the pH was adjusted to pH=8 with saturated sodium bicarbonate solution then extracted with dichloromethane and then washed with brine. The organic extracts were dried over anhydrous sodium sulfate, filtered, and concentrated under reduced pressure. Purification by silica gel chromatography (MeOH/DCM) yielded (5-(2-methyl-2-(methyldisulfanyl)propylamino)-1,3-phenylene)dimethanol (3 g, 65percent) as a white solid. 1H NMR (400 Hz, CDCl3): delta6.62 (s, 1H), 6.54 (s, 2H), 4.53 (s, 4H), 3.13 (s, 2H), 2.30 (s, 3H), 1.32 (s, 6H). See FIG. 47.
 

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