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Chemical Structure| 68235-96-1 Chemical Structure| 68235-96-1

Structure of 68235-96-1

Chemical Structure| 68235-96-1

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Product Details of [ 68235-96-1 ]

CAS No. :68235-96-1
Formula : C8H6ClNO
M.W : 167.59
SMILES Code : O=C1NC2=C(C=CC=C2)C1Cl

Safety of [ 68235-96-1 ]

Application In Synthesis of [ 68235-96-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 68235-96-1 ]

[ 68235-96-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 68235-96-1 ]
  • [ 399-25-7 ]
  • (R)-3-chloro-3-((S)-1-(2-fluorophenyl)-2-nitroethyl)indolin-2-one [ No CAS ]
  • C16H12ClFN2O3 [ No CAS ]
YieldReaction ConditionsOperation in experiment
With C49H35F6N3O2; In dichloromethane; at 20℃; for 24h; General procedure: To a solutionof 3-chloroxindole (1a, 0.3 mmol, 50.3 mg) and catalyst VIII(0.015 mmol, 12.2 mg) in CH2Cl2 (3.0 mL) was added β-nitrostyrene (2a, 0.45 mmol, 67.1 mg). Reaction mixture was stirred for 1 day at room temperature, concentrated, andpurified by flash column chromatography (CH2Cl2:EtOAc= 20:1) to afford the Michael adduct (3a, 83 mg, 83%).
 

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