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Chemical Structure| 68325-20-2 Chemical Structure| 68325-20-2

Structure of 68325-20-2

Chemical Structure| 68325-20-2

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Product Details of [ 68325-20-2 ]

CAS No. :68325-20-2
Formula : C9H8F12O3
M.W : 392.14
SMILES Code : OC(CC(O)CC(O)(C(F)(F)F)C(F)(F)F)(C(F)(F)F)C(F)(F)F
MDL No. :MFCD01723779

Safety of [ 68325-20-2 ]

Application In Synthesis of [ 68325-20-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 68325-20-2 ]

[ 68325-20-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 381-98-6 ]
  • [ 68325-20-2 ]
  • C13H9F15O4 [ No CAS ]
YieldReaction ConditionsOperation in experiment
With sulfuric acid; at 80℃; for 2h; [SYNTHESIS EXAMPLE 3]; Synthesis of 2-trifluoromethylacrylate represented by the following formula (9); Concentrated sulfuric acid (0.50g, 5.10mmol) was added dropwise at room temperature to a mixture of the crude product (1.00g, 2.55mmol) of the formula (7) and 2-trifluoromethylacrylic acid (0.71g, 5.10mmol), followed by stirring at 80C for 2hr. By an analysis of the reaction liquid by gas chromatography, conversion to the formula (9) was 82.0%, and the raw material alcohol (7) was in 13.1%. The reaction liquid was poured into iced water, followed by extraction of the organic matter with diethyl ether. Then, the organic layer was washed with saturated sodium hydrogencarbonate aqueous solution, pure water and saturated brine, followed by drying with magnesium sulfate anhydride. Then, the solvent was removed by evaporator, followed by a separation purification by silica gel column chromatography to obtain the formula (9) (0.82g, 1.59mmol, purity: 92.3GC%) as a colorless, transparent liquid.
 

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