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Chemical Structure| 6914-74-5 Chemical Structure| 6914-74-5

Structure of 6914-74-5

Chemical Structure| 6914-74-5

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Product Details of [ 6914-74-5 ]

CAS No. :6914-74-5
Formula : C5H7NO3
M.W : 129.11
SMILES Code : O=C(C1(C(N)=O)CC1)O
MDL No. :MFCD00190650
InChI Key :SDHXFKBMHSJXHA-UHFFFAOYSA-N
Pubchem ID :2733272

Safety of [ 6914-74-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 6914-74-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 6914-74-5 ]

[ 6914-74-5 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 6914-71-2 ]
  • [ 22059-21-8 ]
  • [ 6914-74-5 ]
YieldReaction ConditionsOperation in experiment
With hydrogenchloride; sodium hydroxide; ammonia; In methanol; Example (2) Preparation of 1-aminocarbonylcyclopropanecarboxylic Acid Ammonia (20 l/h) is passed at 20° C. into a solution of 1,106 g (7 mol) of dimethyl cyclopropane-1,1-dicarboxylate in 700 ml of methanol, with stirring. After approximately 10 hours, addition of NH3 is stopped. 1.4 l of 20percent sodium hydroxide solution are added to the suspension, and the mixture is heated to 40° C. The methanol is distilled off in vacuo. When the mixture is cold, 680 g of concentrated hydrochloric acid are added, whereupon the product precipitates. It is filtered off with suction, washed with cold water and dried (m.p.: 182° C.). Yield: 813 g, 90percent. If it is intended to degrade the 1-aminocarbonylcyclopropanecarboxylic acid to give ACC, then neutralizing with hydrochloric acid is not necessary.
  • 2
  • [ 6914-79-0 ]
  • [ 6914-74-5 ]
YieldReaction ConditionsOperation in experiment
89% With dihydrogen peroxide; sodium hydroxide; at 20℃; for 2h;Cooling; 1-Cyanocyclopropanecarboxylic acid (18.90 g, 170 mmol) was added to a cold solution of NaOH (8.00 g, 200 mmol). The mixture wasallowed to warm to room temperature and 50percent hydrogen peroxide (30 ml) was added in small portions in 2 h. The reaction mixture wasstirred for additional 1 h, acidified until pH 1 and filtered. The residue was dried in vacuo to give the desired product (19.86 g, 89percent).
 

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