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Chemical Structure| 691905-27-8 Chemical Structure| 691905-27-8

Structure of 691905-27-8

Chemical Structure| 691905-27-8

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Product Details of [ 691905-27-8 ]

CAS No. :691905-27-8
Formula : C15H16O
M.W : 212.29
SMILES Code : CC1=C(C2=CC(CO)=CC=C2)C(C)=CC=C1
MDL No. :MFCD20233048

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Application In Synthesis of [ 691905-27-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 691905-27-8 ]

[ 691905-27-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 691905-26-7 ]
  • [ 691905-27-8 ]
YieldReaction ConditionsOperation in experiment
17% With methanol; sodium tetrahydroborate; at 0 - 20℃; for 3.16667h; To a stirred solution of Compound l-2a in methanol (7.5 g, 35.68mmol), NaBH (4.06g, 107.4mmol) was added portion-wise at 0C over a period of 10 min. The reaction temperature was raised to RT and stirred for additional 3 h. After completion of the reaction, the reaction mixture was quenched with saturated ammonium chloride solution, then distilled out methanol completely and diluted with water and extracted with ethyl acetate for 2 times. The organic layer was washed with sat. NaCl solution, dried over Na2S04 and concentrated to afford the crude product. The crude compound was purified by column chromatography on silica gel (100- 200 mesh) using 8-10% of ethyl acetate in pet ether as an eluent to afford Compound l-2b(1.3g, 17%). NMR (400 MHz, CDC13): d 7.45-7.40 (m, 1H), 7.38-7.32 (m, 1H), 7.18-7.05 (m, 5H), 4.74 (d, 2H), 2.02 (s, 6H), 1.64 (t, 1H)
 

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