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Chemical Structure| 693213-58-0 Chemical Structure| 693213-58-0

Structure of 693213-58-0

Chemical Structure| 693213-58-0

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Product Details of [ 693213-58-0 ]

CAS No. :693213-58-0
Formula : C6H11NO2
M.W : 129.16
SMILES Code : O=C(OC)[C@@H](N)C1CC1
MDL No. :MFCD06200656

Safety of [ 693213-58-0 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314-H226
Precautionary Statements:P501-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P362+P364-P303+P361+P353-P332+P313-P403+P235
Class:8(3)
UN#:2920
Packing Group:

Application In Synthesis of [ 693213-58-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 693213-58-0 ]

[ 693213-58-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 138326-68-8 ]
  • [ 693213-58-0 ]
YieldReaction ConditionsOperation in experiment
19.1 g With sodium carbonate; In water; The hydrochloride salt LS3-1 was dissolved in an aqueous solution of Na2CO3 (1 M, 275 mE, 0.272 mol, 1.5 eq). The basic aqueous phase was saturated with NaC1 and extracted with AcOEt/CH2C12 (2:1) (5x1.00 mE). TEC [MeOH/NH4OH/AcOEt (10:2:88); detection: ninhydrin; R1=0.50]. The combined organic phases were dried over Mg504, filtered and concentrated under low vacuum at room temperature to give free amino-ester E53-3 as a yellow oil (19.1 g, 85%, 2 steps). E53-3is volatile and should not be lefi on a mechanical vacuum pump for extended periods of time. To minimize diketopiperazine formation, Step E53-4 should occur immediately after isolation of E53-3. ?H NMR (CDC13): oe 3.70 (3H, s, C130), 2.88-2.85(1H, d, NH2CHCH3O), 1.54 (1H, s, NH2), 1.04-0.97 (1H, m,CH(CH2)2), 0.56-0.27 (4H, m, CH(C)2).
 

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