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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
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Inaccessible (Haz class 6.1), International USD 150+
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Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 69342-47-8 Chemical Structure| 69342-47-8

Structure of 69342-47-8

Chemical Structure| 69342-47-8

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Product Details of [ 69342-47-8 ]

CAS No. :69342-47-8
Formula : C11H13NO
M.W : 175.23
SMILES Code : CCCCC1=CC=C(N=C=O)C=C1
MDL No. :MFCD00013882

Safety of [ 69342-47-8 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H331-H341
Precautionary Statements:P201-P202-P261-P264-P270-P271-P280-P302+P352-P304+P340-P308+P313-P310-P330-P361-P403+P233-P405-P501
Class:6.1
UN#:2206
Packing Group:

Application In Synthesis of [ 69342-47-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 69342-47-8 ]

[ 69342-47-8 ] Synthesis Path-Downstream   1~5

  • 1
  • [ 69342-47-8 ]
  • [ 98-32-8 ]
  • 3-(3-(4-butylphenyl)ureido)-4-hydroxybenzenesulfonamide [ No CAS ]
  • 2
  • [ 69342-47-8 ]
  • [ 22259-53-6 ]
  • 1-((1H-indol-3-yl)methyl)-3-(4-butylphenyl)urea [ No CAS ]
  • 3
  • [ 2124-47-2 ]
  • [ 69342-47-8 ]
  • 1-(4-butylphenyl)-3-(2,4-dimethyl-5-nitrophenyl)urea [ No CAS ]
  • 4
  • [ 28466-26-4 ]
  • [ 69342-47-8 ]
  • C14H18N4O [ No CAS ]
YieldReaction ConditionsOperation in experiment
With triethylamine; In tetrahydrofuran; at 20℃; for 2h; General procedure: 3 -Phenyl- lH-pyrazol-4-amine (100.0 mg, 0.6 mmol, 1.0 equiv) was dissolved in THF (15.0 mL). TEA (l27. l mg, 1.3 mmol, 2.0 equiv) and l-butyl-4-isocyanatobenzene (132.1 mg, 0.8 mmol, 1.2 equiv) were added dropwise. The solution was then stirred for 2 hours at RT. The resulting solution was concentrated under vacuum. The crude product was purified by Prep-HPLC with the following conditions: Column: XBridge Prep OBD C18 Column, 30x l50mm 5um; Mobile Phase A:Water (10 MMOL/L NH4HCO3), Mobile Phase B:ACN; Flow rate:60 mL/min; Gradient:50% B to 82% B in 7.5 min; UV 254/210 nm; RTl :4.48. l-(4-Butylphenyl)-3-(3-phenyl-lH-pyrazol-4-yl)urea (30 mg, 14.3%) was isolated as a white solid. LCMS Method G, MS-ESI: 335. l[M+H+]
  • 5
  • [ 1128-56-9 ]
  • [ 69342-47-8 ]
  • C20H22N4O [ No CAS ]
YieldReaction ConditionsOperation in experiment
With triethylamine; In tetrahydrofuran; at 20℃; for 2h; General procedure: 3 -Phenyl- lH-pyrazol-4-amine (100.0 mg, 0.6 mmol, 1.0 equiv) was dissolved in THF (15.0 mL). TEA (l27. l mg, 1.3 mmol, 2.0 equiv) and l-butyl-4-isocyanatobenzene (132.1 mg, 0.8 mmol, 1.2 equiv) were added dropwise. The solution was then stirred for 2 hours at RT. The resulting solution was concentrated under vacuum. The crude product was purified by Prep-HPLC with the following conditions: Column: XBridge Prep OBD C18 Column, 30x l50mm 5um; Mobile Phase A:Water (10 MMOL/L NH4HCO3), Mobile Phase B:ACN; Flow rate:60 mL/min; Gradient:50% B to 82% B in 7.5 min; UV 254/210 nm; RTl :4.48. l-(4-Butylphenyl)-3-(3-phenyl-lH-pyrazol-4-yl)urea (30 mg, 14.3%) was isolated as a white solid. LCMS Method G, MS-ESI: 335. l[M+H+]
 

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