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Chemical Structure| 69545-37-5 Chemical Structure| 69545-37-5

Structure of 69545-37-5

Chemical Structure| 69545-37-5

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Product Details of [ 69545-37-5 ]

CAS No. :69545-37-5
Formula : C15H15BrO2
M.W : 307.18
SMILES Code : BrC(C1=CC=C(OC)C=C1)C2=CC=C(OC)C=C2
MDL No. :MFCD16361431

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Application In Synthesis of [ 69545-37-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 69545-37-5 ]

[ 69545-37-5 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 2346-00-1 ]
  • [ 69545-37-5 ]
  • [ 1443765-57-8 ]
  • 2
  • [ 35553-92-5 ]
  • [ 69545-37-5 ]
  • [ 1454797-98-8 ]
YieldReaction ConditionsOperation in experiment
63% General procedure: N,N-Diisopropylamine (3.9 mmol) and THF (10 mL) were added to an oven dried 50 mL RB flask under N2 atm. The mixture was cooled to 0 C. n-BuLi (3.85 mmol, 1.6 M solution in hexanes) was slowly added to the above solution under N2 atm then was stirred for 30 min at the same temperature. The flask was cooled to -78 C and ester 5 (3.1 mmol) in THF (5 mL) was slowly added. The mixture was stirred for 15 min at the same temperature. Then, the intermediate bromo compound (0.77 mmol) in THF (5 mL) was added. The mixture was stirred at -78 C for 30 min. On completion, the reaction mixture was allowed to warm to 0 C, quenched with cold water and extracted into ethyl acetate. The organic layer was dried with anhydrous Na2SO4 and the volatiles were evaporated. The crude compound was purified by column chromatography (30% EtOAc/hexane) to afford compound 6aa'.
  • 4
  • [ 69545-37-5 ]
  • [ 2456-81-7 ]
  • C24H27N2O2(1+) [ No CAS ]
 

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