Alternatived Products of [ 706820-95-3 ]
Product Details of [ 706820-95-3 ]
CAS No. : | 706820-95-3 |
MDL No. : | MFCD18384175 |
Formula : |
C16H26BNO4S
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | VSJNPEGKWGUNOP-UHFFFAOYSA-N |
M.W : |
339.26
|
Pubchem ID : | 58169119 |
Synonyms : |
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Safety of [ 706820-95-3 ]
Application In Synthesis of [ 706820-95-3 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 706820-95-3 ]
- 1
-
[ 308283-47-8 ]
-
[ 73183-34-3 ]
-
[ 706820-95-3 ]
Yield | Reaction Conditions | Operation in experiment |
|
With potassium acetate;(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; at 90℃; for 2h;Inert atmosphere; |
Step 2. A flask charged with <strong>[308283-47-8]3-bromo-N-tert-butylbenzenesulfonamide</strong> obtained in step 1 (2.3 g, 7.83 mmol, 1.0 eq), pinacol-dibrane (3.98 g, 15.66 mmol, 2.0 eq), KOAc (2.31 g, 23.49 mmol, 3.0 eq) and Pd (dppf)2Cl2 (640 mg, 0.78 mmol, 0.1 eq) was flushed with nitrogen followed by the addition of 1 ,4-dioxane (20 mL). The mixture was stirred and heated to 9O0C for 2 hours, cooled to room temperature and diluted with EtOAc. The mixture was filtered over a pad of silica gel. The filtrate was concentrated. To the residue, petroleum ether was added. The emerged solid was filtered off. The filtrate was concentrated. The residue was purified by silica gel chromatography to give N-tert-butyl-3-(4,4,5,5-tetramethyl-l,3,2-dioxaborolan-2-yl)benzenesulfonamide (2.32 g, 90% over 2 steps). LC-MS (m/z) - 284.1 [M-56+H]+. |