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Chemical Structure| 7189-08-4 Chemical Structure| 7189-08-4

Structure of 7189-08-4

Chemical Structure| 7189-08-4

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Product Details of [ 7189-08-4 ]

CAS No. :7189-08-4
Formula : C10H10N2O
M.W : 174.20
SMILES Code : OCC1=NN(C2=CC=CC=C2)C=C1
MDL No. :MFCD16613812

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Application In Synthesis of [ 7189-08-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 7189-08-4 ]

[ 7189-08-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 7189-08-4 ]
  • [ 40261-59-4 ]
YieldReaction ConditionsOperation in experiment
45% With sulfur trioxide pyridine complex; triethylamine; In dichloromethane; dimethyl sulfoxide; at 0℃; for 3h; 500 mg (2.9 mmol) of 2- (l-phenyl-lH-pyrrazole-3-yl)-methanol and 0.8 ml (5.7 mmol) of triethylamine were stirred in 10 ml of dichloromethane at 0C. 690 mg (4.3 mmol) of sulfur trioxide pyridine was dissolved in 5 ml of dimethylsulfoxide and the resulting solution was added to reaction solution. After 3 hours later, ethylacetate was added thereto, followed by washing with water. The organic solution thus obtained was dried over anhydrous magnesium sulfate, and the residue was purified by column chromatography to obtain 220 mg of the title compound in a yield of 45%. NMR : lH-NMR (CDCl3) 6 9.98 (1H, s), 8.44 (1H, s), 8.17 (1H, s), 7. 74-7. 71 (2H, m), 7. 53-7. 49 (2H, m), 7. 42-7. 38 (1H, m) Mass (EI) 173 (M++1)
 

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