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Chemical Structure| 72084-13-0 Chemical Structure| 72084-13-0

Structure of 72084-13-0

Chemical Structure| 72084-13-0

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Product Details of [ 72084-13-0 ]

CAS No. :72084-13-0
Formula : C13H11NO2
M.W : 213.23
SMILES Code : O=C(N)C1=CC=CC=C1OC2=CC=CC=C2
MDL No. :MFCD02625470

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Application In Synthesis of [ 72084-13-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 72084-13-0 ]

[ 72084-13-0 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 6476-32-0 ]
  • [ 72084-13-0 ]
  • [ 2243-42-7 ]
  • 2
  • [ 72084-13-0 ]
  • [ 6476-32-0 ]
YieldReaction ConditionsOperation in experiment
61% With triethylamine; ethanaminium,N-(difluoro-lambda4-sulfanylidene)-N-ethyl-,tetrafluoroborate; In ethyl acetate; at 20℃; for 5h;Inert atmosphere; General procedure: To a solution of the aldoxime or the amide (1.0 mmol) and Et3N (1.5mmol) in EtOAc (1 mL, 1 M) at r.t. was added XtalFluor-E8 (1.1 mmol)portionwise over ca. 2 min. The resulting solution was stirred at r.t.for 1 h. The reaction mixture was quenched with sat. aq Na2CO3 and extracted with CH2Cl2 (2 × 10 mL). The combined organic layers were washed with H2O and brine, dried (MgSO4), and concentrated under vacuum to afford the crude nitrile, which was purified by flash chromatography, if required.
 

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