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Chemical Structure| 733783-33-0 Chemical Structure| 733783-33-0

Structure of 733783-33-0

Chemical Structure| 733783-33-0

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Product Details of [ 733783-33-0 ]

CAS No. :733783-33-0
Formula : C13H18N2O2
M.W : 234.29
SMILES Code : O=C(OC)C1=CN=C(CN2CCCCC2)C=C1

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Application In Synthesis of [ 733783-33-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 733783-33-0 ]

[ 733783-33-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 110-89-4 ]
  • [ 10165-86-3 ]
  • [ 733783-33-0 ]
YieldReaction ConditionsOperation in experiment
74% With sodium tris(acetoxy)borohydride; In dichloromethane; for 18h; To a solution of <strong>[10165-86-3]6-formyl-nicotinic acid methyl ester</strong> (0.200 g, 1.21 mmol) and piperidine (0.14 mL, 1.33 mmol) in DCM (15 mL) was added NaB(OAc)3H (0.380 g, 1.80 mmol). After 18 h, the reaction was diluted with 1 N NaOH (10 mL) and extracted with DCM (2*50 mL). The organic layers were combined, dried (Na2SO4), and concentrated. Chromatography of the residue (SiO2; 1-3percent 2 M NH3 in MeOH/DCM) gave the title compound as an oil (0.210 g, 74percent).
 

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